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The Kansas City Chiefs are set to face the N.Y. Giants on September 21, 2025, in a thrilling Sunday night football matchup at MetLife Stadium in East Rutherford, NJ. The Chiefs, led by star quarterback Patrick Mahomes, are looking to bounce back after a string of losses. Mahomes, known for his exceptional pass offense, will be up against the Giants' robust pass defense. The Giants, with Russell Wilson at the helm, aim to exploit Kansas City's recent defensive woes. Wilson, although not as flashy as Mahomes, has been consistent in executing plays, making this a compelling quarterback duel.
Both teams have struggled recently, with Kansas City holding a 0-2 record and the Giants also winless. However, the Giants' pass rush may pose a significant threat to Mahomes, especially with Kansas City's pass protection showing vulnerabilities. The Chiefs' run offense, spearheaded by Isiah Pacheco, might find it challenging against the Giants' solid run defense.
The point spread is set at -6 for Kansas City, with total points at 45. With the Chiefs as favorites, bettors might find value in the Giants covering the spread, considering their strong ATS performance. The game will be broadcasted on NBC, providing ample opportunity for fans to catch the action live.
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![]() Tennessee 0-274% +4½ -118FanDuel | |||||||
Carolina 0-280% +5½ -109BetRivers | |||||||
![]() Washington 1-132% -3½ +100Caesars | |||||||
Cleveland 0-277% +8 -110BetMGM | |||||||
Minnesota 1-146% -2½ -130BetMGM | |||||||
Philadelphia 2-044% -3 -125Caesars | |||||||
New England 1-164% +1½ -105Caesars | |||||||
![]() Tampa Bay 2-018% -6½ -110FanDuel | |||||||
Jacksonville 1-162% -1½ -110Bet365 | |||||||
![]() L.A. Chargers 2-028% -2½ -114BetRivers | |||||||
Seattle 1-123% -7½ -105Bet365 | |||||||
![]() Chicago 0-281% +1½ -115FanDuel | |||||||
![]() San Francisco 2-047% -2½ -110BetRivers | |||||||
![]() N.Y. Giants 0-279% +6½ -110BetMGM | |||||||
![]() Baltimore 1-129% -4½ -110Caesars | |||||||
Buffalo 3-031 -11 -110Bet365 |
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