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The Kansas City Chiefs are set to face off against the N.Y. Giants Giants on September 21, 2025, in a Sunday night football showdown at MetLife Stadium in East Rutherford, NJ. This NFL clash is gearing up to be an exciting event, with the Chiefs entering as the favorites with a point spread of -6 -115, while the Giants are the underdogs at +6 -105 according to Caesars. The over/under is set at 45 points, with both sides priced at -110.
The Chiefs, known for their explosive offense, will look to capitalize on their strong form, while the Giants aim to leverage their home-field advantage. With the game broadcasted on NBC, fans can expect a thrilling encounter. The best odds for Kansas City stand at -335 on the moneyline at Caesars, while the Giants offer a tempting +260, making this a must-watch for bettors.
For those eager to make informed decisions, exploring the point spread could be beneficial, as it provides insights into how the teams are expected to perform against each other. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Don't miss out on the action and check out the latest NFL odds for more betting options.
Stay tuned to our NFL standings page to keep track of how these teams are performing throughout the season.
![]() Tennessee 0-272% +4½ -118FanDuel | |||||||
Carolina 0-278% +5½ -110Bet365 | |||||||
![]() Washington 1-137% -3 -105Caesars | |||||||
Cleveland 0-278% +8 -110BetMGM | |||||||
Minnesota 1-151% -3 -105BetMGM | |||||||
Philadelphia 2-044% -3 -125Caesars | |||||||
New England 1-160% +2 -110Caesars | |||||||
![]() Tampa Bay 2-019% -6½ -110Caesars | |||||||
Jacksonville 1-161% -1½ -110Caesars | |||||||
![]() L.A. Chargers 2-031% -2½ -118BetRivers | |||||||
Seattle 1-120% -7½ -105Bet365 | |||||||
![]() Chicago 0-281% +1½ -110FanDuel | |||||||
![]() San Francisco 2-051% -2 -109BetRivers | |||||||
![]() N.Y. Giants 0-277% +6½ -110BetMGM | |||||||
![]() Baltimore 1-129% -4½ -110Caesars | |||||||
Buffalo 3-031 -11 -110Bet365 |
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