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Before the highly anticipated NFL matchup between the Washington Commanders and the L.A. Chargers on October 5, 2025, sports bettors and fans alike are gearing up for a thrilling showdown at SoFi Stadium in Inglewood, CA. The Commanders, led by Marcus Mariota in place of the injured Jayden Daniels, are looking to bounce back from their recent loss to the Atlanta Falcons. Meanwhile, Justin Herbert and the Chargers aim to continue their strong start to the season, boasting a 3-1 record. Key to this game will be the Commanders' ability to contain Herbert's explosive passing offense, which averages 249 yards per game. On the other side, the Chargers' defense will need to step up against Washington's run game, which has been effective with 154.75 rushing yards per game. Betting trends show the Chargers as favorites, with a -2.5 spread at sportsbooks like Caesars. As the game airs on FOX, fans can expect a competitive clash that could sway betting odds. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() L.A. Rams 3-154% -5½ -105FanDuel | |||||||
Cleveland 1-342% +3½ -109BetRivers | |||||||
Carolina 1-3100% +1½ -108Caesars | |||||||
![]() N.Y. Jets 0-4- +2½ +100Bet365 | |||||||
![]() Indianapolis 3-123% -6½ -110Bet365 | |||||||
Philadelphia 4-00% -4½ -105Caesars | |||||||
New Orleans 0-447% +1 -125BetMGM | |||||||
![]() Baltimore 1-319% -3½ +108Caesars | |||||||
Arizona 2-241% -8½ -110Bet365 | |||||||
Seattle 3-160% -3 -115BetRivers | |||||||
![]() Cincinnati 2-2- +9½ -105Bet365 | |||||||
![]() L.A. Chargers 3-142% -2½ -118BetMGM | |||||||
Buffalo 4-016% -7½ -110Caesars | |||||||
Jacksonville 3-181% +3½ -115Caesars |
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