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The New England Patriots are set to face the New Orleans Saints on October 12, 2025, at the Caesars Superdome in New Orleans, LA. This NFL matchup promises a thrilling encounter as both teams bring unique strengths to the field. The Patriots, led by quarterback Drake Maye, have shown a solid pass offense, averaging 241.4 passing yards per game. However, the Saints' defense, known for its resilience, will be a formidable challenge. The Saints' quarterback Spencer Rattler will look to exploit the Patriots' defense, which has allowed an average of 242.2 passing yards. With the Patriots favored at -3.5 according to the point spread, bettors should consider their strong away record when wagering. The game will also feature prominent players like Alvin Kamara for the Saints and Stefon Diggs for the Patriots. With an over/under set at 46 points, this game is expected to be closely contested. Fans can catch the action live on CBS. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() N.Y. Giants 1-477% +7½ -110FanDuel | |||||||
![]() N.Y. Jets 0-584% +7½ -115Caesars | |||||||
![]() Pittsburgh 3-137% -5 -109BetRivers | |||||||
![]() Indianapolis 4-18% -6½ -105FanDuel | |||||||
![]() Baltimore 1-479% +7½ -109Caesars | |||||||
Jacksonville 4-10% +1½ -118Caesars | |||||||
Carolina 2-394% +3½ -112BetRivers | |||||||
Miami 1-488% +4½ -104FanDuel | |||||||
New Orleans 1-488% +3½ -105FanDuel | |||||||
![]() Las Vegas 1-431% -4½ -110Bet365 | |||||||
![]() Tampa Bay 4-124% -3 -105FanDuel | |||||||
Green Bay 2-1-112% -14½ -105BetMGM | |||||||
![]() Kansas City 2-3100% +1 -110BetMGM | |||||||
![]() Atlanta 2-291% +4 -112BetRivers | |||||||
![]() Washington 3-217% -4½ -105FanDuel |
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