Oct 12, 2025 1:00 PM EDT

Week 6

New England

1-4

New Orleans

-3½ (-105)o45½ (-110)

CBS

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New England Patriots vs New Orleans Saints Picks

Updated:Oct 11, 2025 3:18 AM EDT

Before the highly anticipated NFL clash on October 12, 2025, between the New England Patriots and the New Orleans Saints at Caesars Superdome in New Orleans, LA, fans and bettors alike are buzzing with excitement. This Sunday football game promises to be a thrilling encounter, broadcasted live on CBS. With the Patriots predicted to take a 25-19 victory, our picks highlight New England's strength, boasting a 67.2% win probability. The Saints, despite their home advantage, face a tough challenge.

Our betting tips suggest focusing on the under 46 total points market, which has a favorable expected value (EV) of 5.3%. Historically, our predictions have been spot-on, especially in under bets, with a 57.7% hit rate in recent games. This track record is a testament to our model's accuracy and a boon for bettors looking to make informed decisions.

For those eager to dive deeper into NFL picks, check out our comprehensive NFL picks page. Ready to bet smarter? Explore OddsTrader Turbo now or place your bet with a U.S. regulated sportsbook and profit off the edge.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/129:30 AM Denver 3-2 29% -7 -106BetRivers
N.Y. Jets 0-5 71% +7½ -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Cleveland 1-4 61% +6 -110Bet365
Pittsburgh 3-1 39% -5½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Arizona 2-3 68% +7 -102BetMGM
Indianapolis 4-1 32% -7 -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM L.A. Rams 3-2 34% -7 -112Caesars
Baltimore 1-4 66% +7½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Seattle 3-2 21% +1 -115Bet365
Jacksonville 4-1 79% +1½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Dallas 2-2-1 21% -3 -109Caesars
Carolina 2-3 79% +3 -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM L.A. Chargers 3-2 35% -3½ -113BetRivers
Miami 1-4 65% +4½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM New England 3-2 40% -3½ +100Caesars
New Orleans 1-4 60% +3½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/124:05 PM Tennessee 1-4 65% +4½ -115FanDuel
Las Vegas 1-4 35% -4 -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/124:25 PM San Francisco 4-1 62% +3½ -111Caesars
Tampa Bay 4-1 38% -3 -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/124:25 PM Cincinnati 2-3 68% +14½ -110BetMGM
Green Bay 2-1-1 32% -14½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/128:20 PM Detroit 4-1 67% +2½ -110Caesars
Kansas City 2-3 33% -2 -113SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. MON 10/137:15 PM Buffalo 4-1 16% -4½ -109BetRivers
Atlanta 2-2 84% +5 -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. MON 10/138:15 PM Chicago 2-2 75% +4½ -110Caesars
Washington 3-2 25% -4½ -108BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 10/098:15 PM Philadelphia 4-2 17 -7½ +100BetMGM
N.Y. Giants 2-4 34 +7½ -105BetMGM

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