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As anticipation builds for the upcoming NFL clash on September 21, 2025, between the Pittsburgh Steelers and the New England Patriots at Gillette Stadium in Foxborough, MA, fans and bettors alike are keen to assess the potential impact of the injury report. This game, scheduled for 1:00 PM ET and broadcasted on CBS, sees both teams grappling with significant player injuries that could influence the outcome.
The Steelers are missing key players, including Dean Lowry and Donald Parham Jr., both on injured reserve, which might weaken their defensive line. Additionally, Alex Highsmith is out due to an ankle sprain, potentially leaving a gap in their linebacker core. Meanwhile, the Patriots have Morgan Moses listed as questionable with a foot injury, which could affect their offensive line's performance.
Understanding the nuances of the injury report is crucial for bettors looking to make informed decisions. The absence of core players like Highsmith and the questionable status of Patriots' key players might shift the odds. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more details, check the NFL injuries page.
![]() Tennessee 0-273% +4½ -118FanDuel | |||||||
Carolina 0-280% +5½ -110Bet365 | |||||||
![]() Washington 1-132% -3½ +100Caesars | |||||||
Cleveland 0-277% +8 -110BetMGM | |||||||
Minnesota 1-147% -2½ -130BetMGM | |||||||
Philadelphia 2-042% -3 -125Caesars | |||||||
New England 1-164% +1½ -105Caesars | |||||||
![]() Tampa Bay 2-018% -6½ -110FanDuel | |||||||
Jacksonville 1-162% -1½ -110Bet365 | |||||||
![]() L.A. Chargers 2-029% -2½ -117BetRivers | |||||||
Seattle 1-123% -7½ -105Bet365 | |||||||
![]() Chicago 0-282% +1½ -115FanDuel | |||||||
![]() San Francisco 2-050% -2½ -115BetMGM | |||||||
![]() N.Y. Giants 0-279% +6½ -110BetMGM | |||||||
![]() Baltimore 1-129% -4½ -110Caesars | |||||||
Buffalo 3-031 -11 -110Bet365 |
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