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The eagerly anticipated NFL clash on October 5, 2025, between the New York Giants and the New Orleans Saints at Caesars Superdome in New Orleans, LA, promises to be a game to watch. Both teams are grappling with significant injury concerns, which could influence the outcome and provide savvy bettors with an edge. The Giants are dealing with several key injuries, including Rakeem Nunez-Roches Sr. (foot) and Jevon Holland (neck), both listed as questionable, while Graham Gano (groin) and Chris Board (chest) are on injured reserve. On the Saints' side, Taysom Hill (knee) is on the PUP list, and Cesar Ruiz (ankle) is out for the game. These injuries highlight the importance of keeping an eye on the injury report to make informed betting decisions. The game will be broadcasted on CBS, offering fans a front-row seat to all the action. Be sure to check out our NFL injury report to stay updated. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook to profit off the edge.
![]() L.A. Rams 3-154% -5½ -105FanDuel | |||||||
Cleveland 1-342% +3½ -109BetRivers | |||||||
Carolina 1-3100% +1½ -108Caesars | |||||||
![]() N.Y. Jets 0-4- +2½ +100Bet365 | |||||||
![]() Indianapolis 3-123% -6½ -110Bet365 | |||||||
Philadelphia 4-00% -4½ -105Caesars | |||||||
New Orleans 0-447% +1 -125BetMGM | |||||||
![]() Baltimore 1-319% -3½ +108Caesars | |||||||
Arizona 2-241% -8½ -110Bet365 | |||||||
Seattle 3-160% -3 -115BetRivers | |||||||
![]() Cincinnati 2-2- +9½ -105Bet365 | |||||||
![]() L.A. Chargers 3-142% -2½ -118BetMGM | |||||||
Buffalo 4-016% -7½ -110Caesars | |||||||
Jacksonville 3-181% +3½ -115Caesars |
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