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The upcoming NFL matchup features the San Francisco 49ers visiting the Seattle Seahawks on January 17, 2026, at Lumen Field in Seattle, WA. This Saturday night football game promises an intense battle with plenty of excitement for fans and bettors alike. The 49ers bring a strong pass offense, while the Seahawks boast a formidable pass defense, setting the stage for intriguing game props focused on passing yards and touchdowns. Seattle's run defense will be tested by San Francisco's ground game, and the Seahawks' pass rush will challenge the 49ers' pass protection, factors that could influence totals and prop bets significantly.
Our game projections suggest focusing on the team totals market, where the San Francisco OVER 19.5 points has shown a consistent hit rate with a high expected value (EV) in recent games. Over the last 10 matchups, our prop bets have maintained a positive record, highlighting the value in targeting team props such as field goals and touchdowns. This matchup is broadcast on Fox, giving fans the perfect chance to follow the action live and make informed wagers.
For bettors looking to capitalize on this event, understanding the pace of play and defensive matchups is crucial. The Seahawks' outdoor Lumen Field venue adds an extra layer of complexity, potentially impacting passing efficiency. Check out our detailed NFL player props and league picks pages for expert insights and strategies to maximize your betting potential. Enhance your experience by exploring the best odds at trusted sportsbooks like BetOnline. Dive into the action and make smart bets with our comprehensive coverage of San Francisco 49ers vs Seattle Seahawks game props.
Denver 14-369% +1½ -115Bovada | |||||||
Seattle 14-351% -7½ -103Heritage | |||||||
New England 15-3100% -2½ -120BetOnline | |||||||
![]() Chicago 12-675% +4½ -108Heritage |