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The Arizona Cardinals are set to face the Carolina Panthers in a thrilling NFL matchup at the Bank of America Stadium in Charlotte, NC. Scheduled for December 22, 2024, at 1:00 PM ET, this game promises excitement, especially with the Cardinals having a strong record against the Panthers in recent years. The last encounter saw the Cardinals win 26-16, highlighting their edge in this rivalry. The Cardinals, led by quarterback Kyler Murray, have shown resilience, with a 9-5 ATS record, as seen on our NFL standings page. Meanwhile, the Panthers, with Bryce Young under center, are looking to improve their 3-11 record. The Cardinals are favorites with a -5 point spread, and the total points are set at 47, making it a potential high-scoring affair. The game will be broadcast live on FOX, ensuring fans can catch every moment of the action. With both teams having key players on injury lists, the dynamics could shift, but the Cardinals' recent form makes them a strong contender in this matchup.