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The upcoming clash between the Buffalo Bills and the L.A. Rams promises an exciting matchup at SoFi Stadium, Inglewood, CA, broadcasted live on Fox at 4:25 PM on December 8, 2024. In their last matchup on September 8, 2022, the Bills triumphed with a convincing 31-10 score. With the Bills' strong away record of 4-2 and the Rams' balanced home performance of 3-3, bettors should keep an eye on these stats via our NFL standings page. Currently, the Bills are favored with a -3.5 point spread, according to Caesars. Key players like Josh Allen for the Bills and Matthew Stafford for the Rams could heavily influence the outcome, especially considering recent injuries and lineup changes. The over/under is set at 49.5 points, offering intriguing opportunities for those considering betting on total points. With the Bills' recent victory streak, they appear poised to maintain their momentum against the Rams.