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The upcoming NFL preseason game between the Pittsburgh Steelers and the Carolina Panthers is set to be an exciting matchup at the Bank of America Stadium in Charlotte, NC, on August 21, 2025, at 7:00 PM ET. Broadcast live on CBS and NFL Network, this game will see the Steelers, who won their last matchup against the Panthers 24-16, face off against a Carolina team looking to bounce back from recent losses. With a point spread of -4.5 in favor of the Steelers, bettors are keenly watching the odds. The Panthers' starting quarterback, Bryce Young, is expected to play despite some injuries in the lineup. On the other hand, the Steelers might rely on Aaron Rodgers to lead their offense. The Steelers have a slight edge given their past performance, but the Panthers' home field advantage could come into play. Check out our NFL standings page for more insights into their ATS records.