- Spread
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
FINAL
Sep 14, 2025 1:00 PM EDT
SF 26 vs NO 21
Week 2
SF
-3 (-105)o40½ (-110)
FOXBETCAST
PLAYS
MATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
INJURIES
WEATHER
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
San Francisco 49ers vs New Orleans Saints Picks
Updated:Sep 14, 2025 3:17 AM EDT
Get ready for an exciting clash on September 14, 2025, as the San Francisco 49ers take on the New Orleans Saints at Caesars Superdome in New Orleans, LA. This NFL showdown promises to be thrilling, with both teams eager to make their mark in the league. Our picks suggest a tight game, with the 49ers slightly favored. Our prediction model shows a predicted score of 20-17 in favor of San Francisco, giving them a 59.3% win probability. Notably, our American Total market has a 55.9% hit rate, suggesting a high EV for the under 43.5 bet. Our past predictions have been strong, with a profitable hit rate in the last 10 games. Tune in to FOX for live coverage and don't miss out on placing your bets with a U.S. regulated sportsbook. For more insights, check out our NFL picks page and Start your OddsTrader Turbo subscription to bet smarter.
UPCOMING GAME PREDICTION
Spread
Money
Total
NOSpread
CONSENSUS LINE
+3 (-115)
PROJECTION
NO (17) - SF (20)
COVER PROBABILITY
EXPECTED VALUE
-0.7%
BET RATING
SEASON COVER %
0/1
0%
NFL
Spread
Game
- Game
- 1H
- 2H
- 1Q
- 2Q
- 3Q
- 4Q
NFLSuper Bowl
Download the app© OddsTrader 2026 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader no longer operates under any U.S. license, including Pennsylvania.
Seek help with a gambling addiction at 1-800-Gambler.