Colorado Avalanche vs Buffalo Sabres Picks

Before the much-anticipated NHL showdown between the Colorado Avalanche and the Buffalo Sabres, fans and bettors are buzzing with excitement. Scheduled for October 13, 2025, at the KeyBank Center in Buffalo, NY, this game promises an electrifying atmosphere. Our picks favor the Avalanche, predicting a 4-2 victory over the Sabres. Historically, the Avalanche have a 56% chance of winning, with a high EV despite a negative recent streak. Meanwhile, the Sabres are looking to capitalize on their home advantage, although our predictions suggest a challenging game for them. The Avalanche's powerplay percentage and penalty kill stats give them a slight edge, making them the team to watch. Tune in on alt, msg-b, or espn+ to catch the action live. Considering the Avalanche's strong performance in recent games, our betting tips suggest backing them for a profitable play. For more in-depth NHL predictions, check out our NHL picks.

In recent matchups, the Avalanche have shown resilience, winning 6 out of their last 10 games, with a focus on improving their 5-on-5 play. The Sabres, on the other hand, have struggled with consistency, but their home record remains a factor. Our prediction model highlights the Avalanche's superior hit rate and powerplay efficiency as key factors in their favor. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.