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College Football Odds for Week 0: Aug 23rd

Quarterback Jalon Daniels #6 of the Kansas Jayhawks throws a pass against the Kansas Jayhawks.

Below, we will review the college football odds for Week 0 and determine which of these matchups gives us an interesting point spread on both sides of the equation. This Saturday will usher in the 2025 college football campaign, and after months of waiting, football is officially back!

Iowa State vs. Kansas State (-3)

Saturday, August 23, 2025 – 12:00 PM EDT at Aviva Stadium

Here’s a Big 12 clash that’s worthy of our attention right off the jump. No. 17 Kansas State and No. 22 Iowa State will meet in Dublin, Ireland, at high noon on August 23rd. Those who are familiar with these programs understand that Iowa State has had the upper hand recently, winning four of its last five meetings and covering in every single one.

The opening line saw Kansas State at -3½, but the sharps got down on the dog earlier in the week, to where it now sits at Kansas State -3 at some of the most respected shops like BetMGM and Caesars. Check out the OddsTrader live odds module for up-to-the-second changes.

Idaho State vs. UNLV (-25 ½)

Saturday, August 23, 2025 – 4:00 PM EDT at Allegiant Stadium

This is the second of only five games on Saturday’s Week 0 slate, but if we peruse the line, it appears the squares will be lining up on the Runnin’ Rebs, laying more than three touchdowns and a field goal. The oddsmakers over at BetMGM have UNLV -25½, which makes me think these teams might be playing basketball, but in fact, they will be duking it out on the gridiron.

These schools haven’t met often, but over the last three meetings dating back to 2006, UNLV has handled Idaho State with ease. Their most recent meeting was in 2022, when the Rebels laid the smack down on the Idaho State Bengals and won, 52-21, easily covering as 23-point home chalk.

Will this be just another case of the same thing, or will the Bengals sink their claws into the Rebels and hang tough for four quarters? Make sure to check back in and see where the line has gone throughout the week, and take advantage of that line movement. Tune in and cash a winner!

Fresno State vs. Kansas (-12 ½)

Saturday, August 23, 2025, – 6:30 PM EDT at David Booth Kansas Memorial Stadium

As of this writing, Kansas is favored by 12½ across the board, including at major shops like Caesars and BetMGM. At first blush, this looks like a mismatch, with Kansas hailing from the Big 12 while Fresno State tries to stay relevant in the Mountain West Conference.

However, Fresno State did cover two of its last three games of last season and got to a bowl game, while Kansas ended the season with a 5-7 mark and was blown out by unranked Baylor in its last regular-season game, 45-17.

Naturally, the quality of competition Kansas faced was incrementally better than the level of opposition faced by the Bulldogs, but 12½ points is a lot to give, especially on opening day after a disappointing season. Don’t rule out Fresno State; they could be poised for an upset.

Place a Bet or Start a New Sportsbook Account 

It’s the beginning of a brand-new season, so don’t sit on the sidelines again this year. Open a sportsbook account at a shop you can trust, like Caesars or BetMGM. As a matter of fact, the more outs you have, the more lines at your disposal, and the better off you will be with the ability to shop around and choose the sharpest line available.

Remember, a half-point edge can be the difference between a winner and a loser or a loser and a push. That’s huge! The college football odds are not stagnant. They are dynamic, so if you see a side that you like, then lock those odds and point spreads down. And don’t delay; do it now.

But you’ve got to have sportsbook accounts at your disposal, so check out the current college football odds Week 0 at OddsTrader and find out which side is giving you a serious edge!

*21+ Seek help with a gambling addiction at 1-800-GAMBLER

*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.

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