BETTING

Gonzaga vs. Houston 2025 NCAA Tournament Second Round Pick

Kordelius Jefferson Houston Cougars
Kordelius Jefferson #0 of the Houston Cougars drives to the basket against Eddiean Tirado #40 of the SIU Edwardsville Cougars during the second half in the first round of the NCAA Men's Basketball Tournament at INTRUST Arena on March 20, 2025 in Wichita, Kansas. Jamie Squire/Getty Images/AFP

After an underwhelming first two days of the NCAA Tournament, there should be more excitement with today’s slate of games in college basketball. I asked the AI Model for its favorite bets for the night slate. Here’s what it suggests for you to profit at the top-rated sportsbooks.

NCAAB Pick


Gonzaga Bulldogs vs. Houston Cougars

Saturday, March 22, 2025 – 08:40 PM EDT at INTRUST Bank Arena


The AI Model believes Houston will earn a six-point win against Gonzaga in what could be an epic showdown later tonight. The Cougars are currently -5.5 against the spread and would cover in this scenario.  

Can Houston Stop Gonzaga’s Potent Offense?

The Gonzaga Bulldogs have shot a 56% effective field goal percentage while hitting 35.1% from deep and 57.6% from inside the arc. However, Houston has limited teams to a 44.6% effective field goal percentage and might be one of the only teams in the country that is capable of getting consistent stops defensively against the Zags.

The Cougars also force 21.7% of turnovers and allow just 28.9% of offensive rebounds, making them one of the best defenses in the nation.

Expect Houston To Have More Field Goals

The Cougars have allowed just 6.8% of shots to be blocked this season. On the other hand, Gonzaga has added only 8.3% of blocks.

Ultimately, Houston should be able to get more shots. They’ll likely win the turnover battle and the battle on the glass. Houston does a lot of the little things very well and should do enough to at least get by the Bulldogs in this game.

The Pick

Trust the Model and take Houston at -5.5.

NCAAB Pick: Houston -5.5 (-110) at Bet365

*21+ Seek help with a gambling addiction at 1-800-Gambler

*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.

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