The Top 5 OddsTrader NFL Computer Picks for Week 10

davante adams nfl las vegas raiders
Davante Adams #17 of the Las Vegas Raiders drops a pass in the fourth quarter of the game against the Jacksonville Jaguars. Eric Espada/Getty Images/AFP

With a great lineup for Week 10 in the NFL, we used the OddsTrader BetStation app to find the best computer-generated predictions for this week’s games.

Anyone can download the app for free from their device’s app store. It will show you statistical comparisons of each matchup, information on past meetings as well as spread movement, injury news, and even the weather forecast.

Read on for our top five picks (spreads or totals) from the OddsTrader app for Week 10, including which online sportsbook is offering the best price.


5. Seahawks and Buccaneers Meet in Germany

Our first top pick of Week 10 is the NFL’s first game in Munich, Germany between the Seattle Seahawks (6-3) and Tampa Bay Buccaneers (4-5).

Just about no one would have predicted the Seahawks would have a better record than the Bucs going into this game, but the Seahawks are still a 3-point underdog with a total of 44.5 points.

Can Geno Smith outplay Tom Brady? He did so back in 2013 when he was a rookie with the Jets in a 30-27 win over Brady’s Patriots.


Seattle Seahawks vs. Tampa Bay Buccaneers

Sunday, November 13, 2022 – 09:30 AM EST at Allianz Arena


This spread might be capitalizing on an international game featuring Brady after a comeback win over the Rams last week. The Seahawks have been playing better football than this Tampa Bay team for practically the whole season.

In fact, the Seahawks have won four games in a row by double digits, which is something they did one time during the entire Russell Wilson era. This is with Geno leading the NFL in completion percentage (73.1%) after Week 9, and he is not doing it by dinking and dunking. He is getting the ball down the field and the offense is scoring points (No. 4 scoring offense) unlike the Buccaneers (No. 25) with Brady.

The Seahawks are also getting great running out of rookie back Kenneth Walker III since he took over for the injured Rashaad Penny. Meanwhile, the Buccaneers are dead last in rushing and haven’t had any answers on how to fix that this year.

The Seattle defense may not be as good as Tampa Bay’s defense, but it has played better in recent weeks, holding down the Chargers with Justin Herbert and not allowing the Giants or Cardinals to get much going.

Our Betting Pick

OddsTrader actually likes the Seahawks to win this one by six points. We’ll settle for covering the spread as you never know when that Brady voodoo is going to strike, though

Carroll has gotten the best of Brady in a few matchups before with Seattle wins in 2012 and 2016. This is his first attempt at him in a Tampa Bay uniform.

OddsTrader NFL Final Score Prediction: Seahawks 27 – Buccaneers 21

OddsTrader NFL Total Pick: Seahawks +3 (-115) at Bet365


4. Most Valuable Pat Back in Action vs. Jags

The Kansas City Chiefs won a classic over the Tennessee Titans last week with Patrick Mahomes becoming the fifth quarterback in NFL history to pass for over 400 yards and run for over 60 yards in the same game. What does he have in store for an encore against Jacksonville as he is now the MVP front-runner for the first time in 2022?

The Jaguars are a 9.5-point underdog in a game with a total of 50.5 points.


Jacksonville Jaguars vs. Kansas City Chiefs

Sunday, November 13, 2022 – 01:00 PM EST at GEHA Field at Arrowhead Stadium


The Chiefs are still the No. 1 scoring offense this season at 30.4 points per game, but their scoring has been higher variance than we are used to seeing from Mahomes and Andy Reid.

If you exclude the defense’s pick-six against the Chargers in Week 2 and focus on offensive points, then the Chiefs have four games where they scored 17-to-20 offensive points, three games with 41-plus points (most in the league), and only one game (Raiders) where they finished between 21-to-40 points on offense.

But with an offense that ranks No. 2 on both third down and in the red zone, we expect this to be another one of the high-scoring games. The Jaguars were down 17-0 against the Raiders last week before coming back to win 27-20. The Chiefs had allowed at least 20 points in 12 straight games before getting to play Tennessee rookie quarterback Malik Willis, who led his offense to one first down on the last 10 drives on Sunday night.

But the Titans still moved the ball better than expected, and Jacksonville should be able to score at least 20 points with the way Travis Etienne is running the ball for this team. But the Jaguars do not force enough turnovers or sacks to get after Mahomes and hold him under 30.

Our Betting Pick

The over looks like a great pick in this one as we expect a lot more points than what happened in the Tennessee game, where Mahomes was really tested by the defensive line.

OddsTrader NFL Final Score Prediction: Chiefs 33 – Jaguars 24

OddsTrader NFL Total Pick: Over 50.5 (-105) at MaximBet


3. The NFC North Shootout of the Year?

The Detroit Lions (2-6) may still have the No. 32 defense, but it looked great against Aaron Rodgers last week. The Chicago Bears (3-6) would also love to beat Rodgers and the Packers this year, but they’ll settle for a win at home against the Lions first as the offense continues to improve.

Are we going to get a real shootout in a game where the Bears are a 3-point favorite with a total of 48 points? The weather is expected to be in the high 30s but no real wind or precipitation to mess things up.


Detroit Lions vs. Chicago Bears

Sunday, November 13, 2022 – 01:00 PM EST at Soldier Field


The Lions are an ideal defense for Justin Fields to continue his development. The Lions are the only pass defense allowing over 8.0 yards per pass attempt as they face the deepest passes on average in the NFL. They also have one of the worst pass rushes.

But the Bears are finding their identity and it is still with a strong running game that Fields is heavily involved with. His 178 rushing yards last week are a new record for a regular season game in NFL history, and he was only a few yards shy of Colin Kaepernick’s all-time record set in a playoff game.

The 2022 Bears are the fourth team since 1940 to rush for at least 230 yards in four consecutive games. They could become the first to do it in five straight games as the Lions rank 31st in rushing yards and 28th in yards per carry.

Chicago has scored at least 29 points in three straight games. The Lions are no scoring slouches either, though most of their big games were early in the year. Still, they have some talent at the skill players and Jared Goff has played better than he did in 2021.

Our Betting Pick

This could be the shootout no one saw coming going into the season. But the Lions have been terrible on defense and the Bears have just played 49-29 and 35-32 games the last two weeks.

Let’s go with the over to hit in this one too as OddsTrader’s prediction likes 52 points to be scored.

OddsTrader NFL Final Score Prediction: Bears 27 – Lions 25

OddsTrader NFL Total Pick: Over 48 (-107) at PointsBet


2. Sean McVay Promises Changes (We’ll See)

The loser of this game between the Arizona Cardinals (3-6) and Los Angeles Rams (3-5) will not be returning to the playoffs. Both teams have fallen badly from where they were last year, though Arizona’s decline has been going on longer after that 7-0 start in 2021.

At least the Rams got their ring, because that blown lead in Tampa Bay was inexcusable by Sean McVay to fall to 3-5. The Rams are in must-win mode here and they are only a 1-point home favorite at home as the offense has just not been productive. McVay promises changes, but what are they going to look like?


Arizona Cardinals vs. Los Angeles Rams

Sunday, November 13, 2022 – 04:25 PM EST at SoFi Stadium


This is a nervous game for the Rams since a loss would really destroy any hope this season. If the Cardinals do anything well, it is slowing down Cooper Kupp, the only real bright spot in this offense in 2022. Kupp had 44 yards in the Week 3 meeting between these teams, his only game under 60 yards since 2021 started.

Arizona also has the only other two games since 2021 where Kupp was held under 75 yards. They know how to contain him, though he did score on a 20-yard rushing play in the Week 3 win by the Rams, a 20-12 contest that could have been a bigger blowout if Cam Akers didn’t fumble at the 1-yard line in the fourth quarter.

But the Cardinals also moved the ball somewhat well in that game. They just kept settling for field goals on super long drives of 16-plus plays, which is weird because this offense has been mediocre in the red zone this year. Not great, not terrible. In Week 3, they were terrible. Maybe having DeAndre Hopkins back at wide receiver can help that. He has scored a touchdown in each of the last two games.

But the Rams have owned the Cardinals under McVay. He is 11-1 against this team with every win by at least seven points. He knows he blew last week’s game badly in Tampa.

Our Betting Pick

We like the Rams to show up in this one and complete the season sweep of Arizona.

OddsTrader agrees with the pick of the Rams winning comfortably in the end.

OddsTrader NFL Final Score Prediction: Rams 25 – Cardinals 18

OddsTrader NFL Total Pick: Rams -1 (-107) at PointsBet


1. Josh McDaniels Coaching for His Job vs. Colts’ Ted Lasso Situation

Our favorite pick in Week 10 is a game that could be the biggest comedy or tragedy of the year depending on your perspective. It is hard not to frame this one as Josh McDaniels coaching for his job with the Las Vegas Raiders (2-6) after tying the NFL record by blowing his third 17-point lead of the season. There are nine games left too.

The Colts (3-5-1) just fired their coach Frank Reich after the offense managed a field goal in an ugly 26-3 loss in New England. Then the team shocked the NFL world by bringing former center and current ESPN studio analyst Jeff Saturday into the fold as interim head coach despite no real experience for such a job.

The Raiders are a 6-point favorite at home with a total of 42.5 points. If McDaniels can’t win at home against a lousy team coached by a former player, then how can he keep his job on Monday?


Indianapolis Colts vs. Las Vegas Raiders

Sunday, November 13, 2022 – 04:05 PM EST at Allegiant Stadium


The Colts average a league-low 14.7 points per game. If Matt Ryan was starting this game, then the Colts would have a fighting chance, but Sam Ehlinger still has the job and he has been dreadful. He was sacked nine times in New England. The Raiders lack a pass rush outside of Maxx Crosby, but this could be a game where Crosby eats well all day as the offensive line is awful for Indy.

The Raiders just have this problem of playing one great half and one terrible half. That explains the blown three-score leads to Arizona, Kansas City, and Jacksonville last week. That doesn’t explain the total no-show in the 24-0 loss in New Orleans two weeks ago, but this team should be ready for this one at home. There is still plenty of talent with Davante Adams and Josh Jacobs having fine seasons in spite of quarterback Derek Carr taking a step back from last year.

But the reason to like the Raiders here is that they already beat a better Indianapolis team last year, and this first game experiment for the Colts with Saturday and a new play caller with a replacement-level quarterback could be the disaster of the week in the NFL.

Our Betting Pick

Of course, the Raiders will probably still make it interesting late with the Colts trying to mount a comeback, but this should be a Vegas cover or McDaniels is all but fired this week.

You cannot lose to a guy that was on TV ripping your team a week ago.

OddsTrader NFL Final Score Prediction: Raiders 24 – Colts 17

OddsTrader NFL Spread Pick: Raiders -6 (-105) at PointsBet

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