Buffalo Bills Vs Atlanta Falcons Betting Trends

Before the much-anticipated Monday night football clash on October 13, 2025, between the Buffalo Bills and the Atlanta Falcons at Mercedes-Benz Stadium in Atlanta, GA, excitement is brewing among NFL fans and bettors alike. The Bills, led by star quarterback Josh Allen, are coming off a mixed season start with a 4-1 record, while the Falcons aim to leverage their home advantage with Kirk Cousins at the helm. This matchup is poised to highlight key betting trends, including the Bills' impressive pass offense against the Falcons' struggling pass defense.

With a spread of -3.5 favoring Buffalo, bettors should note the Bills' strong performance in away games, which you can see on our NFL standings page. The Falcons, however, have shown resilience at home and will look to capitalize on Buffalo's occasional defensive lapses. The over/under is set at 50 points, suggesting a potentially high-scoring affair.

In their last matchup on January 2, 2022, the Bills triumphed over the Falcons 29-15. With both teams having adjusted their strategies and rosters since then, this game promises fresh dynamics and opportunities for smart bets. Tune in on ESPN to catch the action live.