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The upcoming Sunday football showdown on December 14, 2025, features the Buffalo Bills visiting the New England Patriots at Gillette Stadium in Foxborough, MA. This NFL Week 15 clash promises intense action as the Bills, led by their starting quarterback Josh Allen, face off against the Patriots, who will start their backup quarterback Drake Maye. Despite Maye being a backup, the Patriots' strong offensive line and defensive stats make them formidable at home.
Buffalo boasts a potent offense averaging 383.7 total yards per game with 225.9 passing yards, while New England counters with a solid defense allowing just 296.4 yards per game. The Bills' dynamic passing game will challenge the Patriots' pass defense, which ranks slightly better in limiting passing first downs. Running backs James Cook III and Rhamondre Stevenson will be key in the run game battle, with the Patriots' rush defense allowing fewer rushing yards per game.
The Patriots hold a strong 11-2 straight-up record and a 9-4 ATS record, indicating their ability to cover the spread at home, while the Bills have a respectable 9-4 SU but a weaker 6-7 ATS record. The current odds favor the Bills by 1.5 points with a total over/under of 48.5. This spread highlights a close contest with a slight edge to the Bills, but the Patriots' home advantage and defensive prowess could keep the game tight.
In their last matchup on October 5, 2025, New England edged Buffalo 23-20, a close game that went under the total points. Key players like Tre'Davious White and Stefon Diggs will be crucial in defense and offense respectively. The game will be broadcast on CBS, offering fans and bettors comprehensive coverage.
Utilizing betting trends and game insights, bettors can leverage the quarterback matchup, offensive and defensive stats, and historical outcomes to make informed wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Houston 8-525% -10 -110BetMGM | |||||||
Philadelphia 8-513% -11½ -120FanDuel | |||||||
Jacksonville 9-430% -13½ -115Caesars | |||||||
![]() Chicago 9-430% -7½ -107Caesars | |||||||
New England 11-253% +1½ -110Bet365 | |||||||
![]() Cincinnati 4-946% +3 -113Caesars | |||||||
![]() Kansas City 6-745% -5½ -110FanDuel | |||||||
![]() N.Y. Giants 2-1133% -2½ -112Caesars | |||||||
Seattle 10-341% -13½ -115Caesars | |||||||
Denver 11-228% +1½ -110FanDuel | |||||||
New Orleans 3-1073% +3 -112Caesars | |||||||
![]() L.A. Rams 10-362% -5½ -117SugarHouse | |||||||
![]() San Francisco 9-412% -12 -113BetRivers | |||||||
Dallas 6-6-125% -5 -120BetMGM | |||||||
![]() Pittsburgh 7-645% -3 -113Caesars | |||||||
![]() Tampa Bay 7-728 -5½ -112SugarHouse |
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