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The upcoming NFL clash on December 14, 2025, between the Indianapolis Colts and Seattle Seahawks at Lumen Field in Seattle, WA, promises to be a thrilling Sunday football showdown. The Seattle Seahawks, favored by 13.5 points with a total points line at 41.5, will host the Colts in this Week 15 regular-season matchup, broadcasted on CBS. The Seahawks enter the game with a strong home record of 4-2 and an impressive 10-3 ATS record overall, while the Colts have a balanced 3-3 ATS record on the road.
Starting quarterbacks Sam Darnold for the Seahawks and Riley Leonard for the Colts are expected to lead their offenses. Seattle's passing offense averages 235.6 yards per game against an Indianapolis passing defense allowing 246.3 yards, suggesting a potential passing battle. The Colts' run offense, averaging 130.9 yards, will face a Seahawks run defense that allows 91.2 yards on average, giving Indianapolis a slight edge on the ground. Meanwhile, Seattle's pass protection and Colts' pass rush could be pivotal, with the Colts averaging 1.8 sacks per game and Seattle allowing 1.3 sacks.
Recent form favors Seattle, who have won their last five games with significant margins and covered the spread in recent outings. Indianapolis has struggled, losing four of their last five. Betting trends indicate Seattle's dominance at home and strong defensive stats, making them the best bet in this matchup. The Seahawks' ability to control the game tempo and capitalize on turnovers could be decisive.
For bettors looking to make informed decisions, these betting trends and game insights provide a solid foundation. The Colts' injury concerns, including key questionable players, might also influence the outcome. Don't miss the action on Sunday night football at Lumen Field, and enhance your betting strategy by checking out our detailed analysis. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on September 12, 2021, the Seahawks defeated the Colts 28-16, showcasing their home advantage and strong defense.
![]() Houston 8-525% -10 -110BetMGM | |||||||
Philadelphia 8-513% -11½ -120FanDuel | |||||||
Jacksonville 9-430% -13½ -115Caesars | |||||||
![]() Chicago 9-430% -7½ -107Caesars | |||||||
New England 11-253% +1½ -110Bet365 | |||||||
![]() Cincinnati 4-946% +3 -113Caesars | |||||||
![]() Kansas City 6-745% -5½ -110FanDuel | |||||||
![]() N.Y. Giants 2-1133% -2½ -112Caesars | |||||||
Seattle 10-341% -13½ -115Caesars | |||||||
Denver 11-228% +1½ -110FanDuel | |||||||
New Orleans 3-1073% +3 -112Caesars | |||||||
![]() L.A. Rams 10-362% -5½ -117SugarHouse | |||||||
![]() San Francisco 9-412% -12 -113BetRivers | |||||||
Dallas 6-6-125% -5 -120BetMGM | |||||||
![]() Pittsburgh 7-645% -3 -113Caesars | |||||||
![]() Tampa Bay 7-728 -5½ -112SugarHouse |
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