Sep 28, 2025 1:00 PM EDT

Week 4

Carolina

1-2

New England

-5½ (-110)o43 (-110)

FOX

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Carolina Panthers Vs New England Patriots Odds

Updated:Sep 24, 2025 4:17 AM EDT

Get ready for some thrilling NFL action as the Carolina Panthers face off against the New England Patriots on September 28, 2025. This regular season Week 4 clash promises to be a captivating encounter at Gillette Stadium in Foxborough, MA, broadcasted live on FOX. The Patriots, playing at home, are favored with a point spread of -5½ -110, while the Panthers are the underdogs at +5½ -110, according to Caesars. The over/under is set at a competitive 43.5 points. With the Patriots' strong home record and the Panthers' determination to prove themselves, this game is set to be a strategic battle. Understanding the odds and betting lines can offer insights into potential outcomes. For those looking to make informed bets, consider the current odds and how they have shifted since opening. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more detailed NFL odds, check our NFL odds page. Don't miss out on what could be a pivotal game in the NFL season.

How can I place a bet on the Panthers vs Patriots game?

Spread (FULL GAME)

EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE

CarolinaSpread

+12.0%

New EnglandSpread

-15.6%

MONEYLINE (FULL GAME)

EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE

CarolinaMONEYLINE

+17.9%

New EnglandMONEYLINE

-21.9%

EXCLUSIVE BOOSTS

Commanders, Buccaneers, Texans & Patriots All WinCommanders, Buccaneers, Texans & Patriots all win

Total (FULL GAME)

EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE

OVERTotal

-7.6%

UNDERTotal

-0.4%

Spread (1H)

BEST LINE

CarolinaSpread

New EnglandSpread

MONEYLINE (1H)

BEST LINE

CarolinaMONEYLINE

New EnglandMONEYLINE

Total (1H)

BEST LINE

OVERTotal

UNDERTotal

Spread (2H)

BEST LINE

CarolinaSpread

New EnglandSpread

MONEYLINE (2H)

BEST LINE

CarolinaMONEYLINE

New EnglandMONEYLINE

DRAWMONEYLINE

Total (2H)

BEST LINE

OVERTotal

UNDERTotal

Spread (1Q)

BEST LINE

CarolinaSpread

New EnglandSpread

MONEYLINE (1Q)

BEST LINE

CarolinaMONEYLINE

New EnglandMONEYLINE

Total (1Q)

BEST LINE

OVERTotal

UNDERTotal

Spread (2Q)

BEST LINE

CarolinaSpread

New EnglandSpread

MONEYLINE (2Q)

BEST LINE

CarolinaMONEYLINE

New EnglandMONEYLINE

Total (2Q)

BEST LINE

OVERTotal

UNDERTotal

Spread (3Q)

BEST LINE

CarolinaSpread

New EnglandSpread

MONEYLINE (3Q)

BEST LINE

CarolinaMONEYLINE

New EnglandMONEYLINE

Total (3Q)

BEST LINE

OVERTotal

UNDERTotal

Spread (4Q)

BEST LINE

CarolinaSpread

New EnglandSpread

MONEYLINE (4Q)

BEST LINE

CarolinaMONEYLINE

New EnglandMONEYLINE

Total (4Q)

BEST LINE

OVERTotal

UNDERTotal

The best odds available today for Carolina is +5½ -109 at BetRivers and for New England -5½ -106 at Caesars. The total for the over/under line is o42½ -115 at Caesars.

NFL

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/289:30 AM Minnesota 2-1 56% -2 -120BetMGM
Pittsburgh 2-1 44% +3 -120SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Philadelphia 3-0 35% -3½ -105FanDuel
Tampa Bay 3-0 65% +3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM New Orleans 0-3 68% +15½ -109Caesars
Buffalo 3-0 32% -15 -120BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Carolina 1-2 60% +5½ -109BetRivers
New England 1-2 40% -5½ -106Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Washington 2-1 27% -1 -105BetMGM
Atlanta 1-2 73% +1½ -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Cleveland 1-2 86% +10 -110Bet365
Detroit 2-1 14% -9½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Tennessee 0-3 75% +7½ -117BetRivers
Houston 0-3 25% -7 -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM L.A. Chargers 3-0 23% -6½ -108BetRivers
N.Y. Giants 0-3 77% +6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:05 PM Jacksonville 2-1 65% +3½ -115Caesars
San Francisco 3-0 35% -3 -117BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:05 PM Indianapolis 3-0 66% +3½ -110Caesars
L.A. Rams 2-1 34% -3 -120SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:25 PM Chicago 1-2 43% +1½ -118FanDuel
Las Vegas 1-2 57% -½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:25 PM Baltimore 1-2 40% -2½ -115Caesars
Kansas City 1-2 60% +3 -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/288:20 PM Green Bay 2-1 39% -6½ -110Caesars
Dallas 1-2 61% +7 -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. MON 09/297:15 PM N.Y. Jets 0-3 70% +3 -115BetRivers
Miami 0-3 30% -2½ -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. MON 09/298:15 PM Cincinnati 2-1 92% +7½ -110Caesars
Denver 1-2 8% -7½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 09/258:15 PM Seattle 3-1 23 -1 -110Caesars
Arizona 2-2 20 +2 -109SugarHouse

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