Betting Trends Tampa Bay Buccaneers vs Carolina Panthers

The upcoming NFL showdown on December 21, 2025, between the Tampa Bay Buccaneers and the Carolina Panthers at Bank of America Stadium in Charlotte, NC, is set to deliver thrilling Sunday football action. The Buccaneers, led by starting quarterback Baker Mayfield, are favored with a -3 point spread and the game total set at 45.5 points. The Panthers will counter with Bryce Young under center, despite some questionable wide receiver health, including Mike Evans listed as questionable for Tampa Bay.

Analyzing the betting trends, Tampa Bay's offense averages 203.4 passing yards per game against Carolina's defense allowing 215.5 yards, suggesting a close battle in the air. The Buccaneers' solid pass rush, averaging 2.36 sacks per game, contrasts with the Panthers' pass protection, which concedes 2.21 sacks, potentially tipping the scales defensively. On the ground, both teams show similar rushing attempts per game, but the Panthers have a slight edge in run defense, which could limit Tampa Bay's ground game.

Recent form sees the Panthers at 5-5 in their last 10 games with a 4-2 home record ATS, while Tampa Bay struggles ATS with a 5-9 record overall but holds a 4-3 away ATS record. The point spread of -3 for Tampa Bay reflects their slight edge, but Carolina's ability to cover at home makes this an enticing matchup for bettors looking for value. The total points line at 45.5 suggests a moderately high-scoring game, but with Tampa Bay's defense allowing 246.9 passing yards and Carolina's offense averaging 183.4 yards, expect some back-and-forth scoring.

For bettors, these betting insights highlight the importance of monitoring health updates and in-game adjustments, especially in the passing game. The Panthers' Bryce Young and Tampa Bay's Baker Mayfield will be key to the betting trends, and the spread offers a solid betting opportunity. Watch for late-breaking news on Tampa Bay's wide receivers and Carolina's defensive line, which could influence the final outcome.

Don’t miss the chance to get the best odds for this exciting NFL matchup. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. See how the teams fared in their last matchup on December 29, 2024, where Tampa Bay won 48-14. For a deeper dive, check out the NFL standings page to track team ATS records and trends.