Nov 30, 2025 1:00 PM EST

Week 13

Houston

8-3

Indianapolis

IND

-4½ (-110)o44½ (-105)

CBS

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Houston Texans vs Indianapolis Colts Odds

Updated:Nov 25, 2025 1:38 AM EST

The upcoming NFL showdown on November 30, 2025, between the Houston Texans and Indianapolis Colts at Lucas Oil Stadium in Indianapolis, IN, is set to be a thrilling Sunday football event. This game, part of the 2025-26 NFL regular season Week 13, is broadcast on CBS, giving fans nationwide a chance to catch the action live.

Current odds favor the Indianapolis Colts as the favorite with a point spread of -4½ -107, while the Houston Texans are the underdogs at +4½ -113. The opening point spread was the same, indicating consistent confidence from sportsbooks. The over/under is set at 44½ with odds of -110 for the over and -109 for the under. These betting lines provide valuable insights into how the teams are expected to perform, helping bettors make informed decisions.

The Colts, playing at home, have the advantage of the retractable dome at Lucas Oil Stadium, which could impact game conditions. Bettors looking for an edge should consider these factors alongside the current odds. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more detailed NFL betting odds, visit our NFL odds page.

When is the Houston Texans vs Indianapolis Colts game?

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/271:00 PM Green Bay 7-3-1 61% +3 -115Bet365
Detroit 7-4 39% -2½ -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/274:30 PM Kansas City 6-5 52% -3 -114Caesars
Dallas 5-5-1 48% +3½ -118BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/278:20 PM Cincinnati 3-8 84% +7 -110BetMGM
Baltimore 6-5 16% -6½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/283:00 PM Chicago 8-3 60% +7 -114Caesars
Philadelphia 8-3 40% -6½ -125BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Houston 6-5 66% +4½ -110BetMGM
Indianapolis 8-3 34% -3½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Arizona 3-8 55% +3 -109Caesars
Tampa Bay 6-5 45% -2½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Jacksonville 7-4 13% -6½ -110Bet365
Tennessee 1-10 87% +6½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM L.A. Rams 9-2 - -10 -110Bet365
Carolina 6-6 - +10½ -109BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM New Orleans 2-9 88% +6 -110BetMGM
Miami 4-7 12% -5½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Atlanta 4-7 20% -2½ -110Bet365
N.Y. Jets 2-9 80% +2½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM San Francisco 8-4 60% -6 -109Caesars
Cleveland 3-8 40% +6½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/304:05 PM Minnesota 4-7 78% +10½ -112BetRivers
Seattle 8-3 22% -10½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/304:25 PM Buffalo 7-4 19% -3½ -115Caesars
Pittsburgh 6-5 81% +4½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/304:25 PM Las Vegas 2-9 80% +9½ -105BetMGM
L.A. Chargers 7-4 20% -9½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/308:20 PM Denver 9-2 13% -6½ -110Bet365
Washington 3-8 87% +6½ -102BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. MON 12/018:15 PM N.Y. Giants 2-10 80% +7½ -115Caesars
New England 10-2 20% -7½ -105Caesars

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