Pittsburgh Steelers vs New England Patriots Betting Trends

As the New England Patriots prepare to face the Pittsburgh Steelers on September 21, 2025, at Gillette Stadium in Foxborough, MA, bettors are keen to explore the betting trends surrounding this matchup. Both teams have shown varying performances this season, with the Patriots standing at a 1-1 record, while the Steelers also mirror this with a 1-1 record. This game promises to deliver an intriguing battle as both teams have strong defensive lines. The Patriots' pass offense, led by Drake Maye, will look to exploit the Steelers' pass defense, which has struggled at times, giving up an average of 245 passing yards per game. However, the Steelers' run defense has been solid, allowing only 62.5 rushing yards per game, which could stifle the Patriots' run game led by Rhamondre Stevenson.

Despite the defensive prowess, the Steelers' offense, led by Aaron Rodgers, has been inconsistent, especially in their passing game, averaging only 206.5 passing yards per game. However, their run game could be a key factor, as it has shown potential with 20.5 rushing attempts per game. The Patriots will need to contain this to avoid giving the Steelers an edge. Historically, the Patriots have had the upper hand in recent matchups, including their December 7, 2023 clash where they won 21-18.

With the Steelers' ATS record of 0-2, bettors might lean towards the Patriots, who are favored with a +1.5 point spread. The total points line is set at 44.5, suggesting a moderately high-scoring game. Catch this exciting NFL matchup on CBS, and for those eager to make an informed bet, Start your OddsTrader Turbo subscription now for the best insights!