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The upcoming clash on September 21, 2025, between the Pittsburgh Steelers and the New England Patriots at Gillette Stadium in Foxborough promises an exciting showdown. The Patriots, led by quarterback Drake Maye, will face off against the Steelers' formidable defense. With the Steelers' Aaron Rodgers at the helm, the game is set to be a battle of strategic plays and dynamic offenses. The Patriots' passing offense, averaging 243.5 yards per game, will be challenged by the Steelers' defense, which has allowed only 206.5 passing yards on average. Conversely, the Steelers' run offense, gaining 62.5 yards per game, will face the Patriots' run defense, which has been relatively effective.
Both teams have shown varying performances in their recent games. The Patriots recently secured a win against the Miami Dolphins, while the Steelers lost to the Seattle Seahawks. In terms of betting insights, the Patriots have a slight edge with a +1.5 spread at Caesars. The total points are set at 44.5, suggesting a potentially high-scoring game. For those looking to make informed bets, the Patriots' recent home performance and the Steelers' away record are crucial considerations. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on December 7, 2023, the Patriots edged out the Steelers with a 21-18 win, showcasing their resilience in close games. As the teams prepare to face each other again, bettors should keep an eye on the Patriots' offensive strategies and the Steelers' defensive setups. For more on how these stats can guide your betting decisions, check out our NFL standings page.
Catch the action live on CBS and make sure to analyze the betting trends and game insights thoroughly to maximize your wagering success.
![]() Tennessee 0-272% +5 -110Bet365 | |||||||
Carolina 0-273% +5½ -115BetMGM | |||||||
![]() Washington 1-144% -3 +100Caesars | |||||||
Cleveland 0-281% +7½ -110BetRivers | |||||||
Minnesota 1-150% -3 -105BetMGM | |||||||
Philadelphia 2-046% -3½ -104FanDuel | |||||||
New England 1-162% +2 -112BetRivers | |||||||
![]() Tampa Bay 2-021% -6½ -110Caesars | |||||||
Jacksonville 1-161% -1½ -108SugarHouse | |||||||
![]() L.A. Chargers 2-031% -2½ -118BetRivers | |||||||
Seattle 1-118% -7 -113Caesars | |||||||
![]() Chicago 0-284% +1½ -110Caesars | |||||||
![]() San Francisco 2-046% -2 -109BetRivers | |||||||
![]() N.Y. Giants 0-275% +6½ -114BetRivers | |||||||
![]() Baltimore 1-132% -4½ -110Caesars | |||||||
Buffalo 3-031 -11 -110Bet365 |
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