San Francisco 49ers vs Philadelphia Eagles Game Props

The upcoming showdown on January 11, 2026, between the San Francisco 49ers and Philadelphia Eagles at Lincoln Financial Field in Philadelphia, PA, is set to kick off the 2025-26 NFL season with a bang. This Sunday football game promises a thrilling clash of offenses and defenses that bettors won't want to miss. The 49ers boast a strong pass offense that will challenge the Eagles' robust pass defense, while Philadelphia's run offense will test San Francisco's run defense. Additionally, the 49ers' pass protection will be crucial against the Eagles' aggressive pass rush, making this a strategic battle on both sides of the ball.

For bettors interested in game props, the player to score first touchdown market offers high EV and a solid hit rate, particularly with Saquon Barkley as a favorite. Our prop bets have performed well over the last 10 games, especially in markets related to touchdowns and field goals, providing valuable insights for this matchup. The pace of play is expected to be moderate, which can influence totals and team props effectively.

Catch the game live on FOX and get the latest odds and analysis to make informed bets. For detailed player props and expert picks, check out our NFL player props and NFL picks pages. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.