Jan 3, 2026 8:00 PM EST

Week 18

Seattle

12-4

San Francisco

SEA

-1 (-110)o49½ (-110)

ABC/ESPN

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Seattle Seahawks vs San Francisco 49ers Picks

Updated:Dec 30, 2025 1:39 AM EST

The upcoming NFL showdown on January 4, 2026, features the Seattle Seahawks facing off against the San Francisco 49ers at Levi's Stadium in Santa Clara, California. This Saturday football event is a pivotal Week 18 regular season game that promises plenty of excitement and strategic betting opportunities. Broadcasted on ABC and ESPN, fans and bettors alike will have prime access to this thrilling contest.

Our expert picks for the Seattle Seahawks vs San Francisco 49ers game lean towards a narrow victory for the Seahawks with a predicted score of 26-23. The point spread is tight with Seattle favored at -1.5, and we predict the total score to hover just under the 49.5 mark. This prediction aligns with a strong hit rate in the 2-way market, where Seattle has shown a profitable 57.7% coverage and a positive EV of 4.8% in recent games.

Recent prediction results highlight our model's strength in point spread bets, especially with Seattle's performance covering 52% of the time with an EV of 0.1%, and the under 49.5 total score bet showing a 51% hit rate. These stats suggest this game offers great value for bettors looking for solid American Total and spread markets.

For bettors looking to enhance their strategy, our NFL picks page offers detailed insights and ongoing updates to help make smart, informed decisions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. SAT 01/034:30 PM Carolina 8-8 58% +3 -120FanDuel
Tampa Bay 7-9 42% -2½ -113Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 01/038:00 PM Seattle 13-3 68% -1 -110Caesars
San Francisco 12-4 32% +1½ -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/041:00 PM Green Bay 9-6-1 25% +6½ -110Caesars
Minnesota 8-8 75% -5½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/041:00 PM Indianapolis 8-8 67% +10½ -114FanDuel
Houston 11-5 33% -10 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/041:00 PM Cleveland 4-12 83% +7½ -107Caesars
Cincinnati 6-10 17% -7½ -107BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/041:00 PM Dallas 7-8-1 25% -4½ -110Bet365
N.Y. Giants 3-13 75% +5½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/041:00 PM New Orleans 6-10 33% +3 -109Caesars
Atlanta 7-9 67% -2½ -117BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/041:00 PM Tennessee 3-13 100% +13 -120BetMGM
Jacksonville 12-4 0% -11½ -110BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/044:25 PM Miami 7-9 100% +11½ -110Bet365
New England 13-3 0% -10½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/044:25 PM Kansas City 6-10 60% -5½ -110Caesars
Las Vegas 2-14 40% +5½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/044:25 PM Detroit 8-8 50% +2½ -105FanDuel
Chicago 11-5 50% -2 -120BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/044:25 PM N.Y. Jets 3-13 91% +7½ -105FanDuel
Buffalo 11-5 9% -7 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/044:25 PM Washington 4-12 100% +8 -120BetMGM
Philadelphia 11-5 0% -7½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/044:25 PM Arizona 3-13 - +9½ -110BetRivers
L.A. Rams 11-5 - -7 -112FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/044:25 PM L.A. Chargers 11-5 67% +12½ -110Bet365
Denver 13-3 33% -11½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/048:20 PM Baltimore 8-8 23% -3½ -105Bet365
Pittsburgh 9-7 77% +3½ -113Caesars

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