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The Buffalo Bills are set to face the Indianapolis Colts on November 10, 2024, at Lucas Oil Stadium in Indianapolis, IN. The game will be broadcast on CBS and begins at 1:00 PM EST. The Bills, who are coming off a narrow win against the Miami Dolphins with a score of 30-27, have been strong on the road with a 3-2 record. Meanwhile, the Colts hold a 3-1 home record and are looking to bounce back after their recent loss to the Minnesota Vikings. Josh Allen, the starting quarterback for the Bills, has been in excellent form, leading his team with impressive offensive stats, including 216.1 passing yards per game. On the other hand, the Colts' defense has been formidable, allowing only 233.8 passing yards per game. The point spread for this matchup is set at -4 in favor of the Bills, and the total points are 46.5. This game will test the Colts' ability to defend their home turf against a high-scoring Bills offense. For more details on how teams rank, check the NFL standings page.