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The upcoming NFL game on December 28, 2025, between the Arizona Cardinals and Cincinnati Bengals at Paycor Stadium in Cincinnati, OH, is setting the stage for an exciting Week 17 showdown. This Sunday football clash offers plenty of betting trends and insights to consider for bettors looking to make informed wagers.
The Cardinals will start QB Kyler Murray, who faces a Bengals defense allowing an average of 246.8 passing yards per game. Cincinnati's defense has been solid against the pass but struggles against the run, giving up 156 rushing yards per game. Arizona's offense averages 235 passing yards and 97 rushing yards per game, while Cincinnati's offense, led by Joe Burrow, puts up 231 passing yards and 88 rushing yards on average.
Key matchup factors include Arizona's pass offense against Cincinnati's pass defense and Cincinnati's run offense versus Arizona's run defense. The Cardinals have some questionable players like WR Marvin Harrison Jr. and CB Will Johnson, but their probable starters should still put up a fight. The Bengals have a few key injuries but maintain a strong lineup.
The current odds favor Cincinnati as a 7-point favorite with a total points line set at 53.5. This spread suggests bettors expect the Bengals to win comfortably, but the over/under indicates a moderately high-scoring game. The Cardinals are 6-9 ATS overall, with a strong 5-2 ATS record on the road, while the Bengals are 7-8 ATS, 3-4 at home, making this a close betting contest.
Recent form shows the Cardinals have struggled lately with several losses, while the Bengals have had mixed results but a strong recent win over Miami. The best odds for Cincinnati are -7 at Caesars, with the Cardinals at +7. For smart bettors looking to capitalize on these betting trends, Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook like Caesars to get the edge.
In their last matchup on October 8, 2023, the Bengals defeated the Cardinals 34-20, showing they can control the game. Check out our NFL standings page for more ATS records and trends to inform your bets.
![]() Cincinnati 5-1031% -7 -108FanDuel | |||||||
Carolina 8-758% +7½ -120FanDuel | |||||||
Cleveland 3-1264% +3½ -110Caesars | |||||||
![]() Tennessee 3-1259% +2½ -114FanDuel | |||||||
Miami 6-984% +5½ -105Caesars | |||||||
![]() Indianapolis 8-758% +6½ -112FanDuel | |||||||
![]() N.Y. Jets 3-1256% +13½ -110Bet365 | |||||||
![]() Las Vegas 2-1369% +2½ -105Bet365 | |||||||
Buffalo 11-432% -1 -112BetRivers | |||||||
![]() San Francisco 11-429% -3 -114BetRivers | |||||||
![]() Atlanta 6-984% +8½ -118FanDuel | |||||||
![]() Washington 4-1223 +9½ -112BetRivers | |||||||
Minnesota 8-823 +7½ -110BetMGM | |||||||
![]() Kansas City 6-1013 +13½ -105BetMGM | |||||||
![]() L.A. Chargers 11-516 -½ -117SugarHouse | |||||||
Green Bay 9-6-124 -2 -117SugarHouse |
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