Buffalo Bills vs Cleveland Browns Player Props

The upcoming NFL matchup on December 21, 2025, between the Buffalo Bills and Cleveland Browns at Huntington Bank Field in Cleveland, OH, is set to deliver an exciting Sunday football experience. This regular season Week 16 game will be broadcast on CBS, giving fans a prime viewing opportunity to catch all the action live.

Both teams bring contrasting strengths to the field, making player props a key area for bettors to explore. Buffalo's passing offense, led by Josh Allen, matches up against Cleveland's pass defense, creating intriguing dynamics for passing yards and completions. Our player projections suggest a high EV player prop bet on Josh Allen going over 217.5 passing yards, which has a solid 52.5% hit rate in recent games. On the other side, Cleveland's Shedeur Sanders faces a tough pass rush, which impacts his passing attempts and completions, making under 15.5 completions a valuable prop bet to consider.

The run game also plays a critical role as Buffalo's run offense and Cleveland's run defense battle for control of the ground game. Pass protection versus pass rush dynamics will shape how many passing attempts and rushing yards key players accumulate, directly influencing prop bets like rushing yards and passing yards.

Our prop bet results over the last 10 games have shown consistent profitability, particularly in markets focused on passing yards and completions, which align well with the current player projections for this event. Bettors can leverage these insights to make informed wagers and maximize their edge.

For those looking to dive deeper into NFL player props, check out our comprehensive NFL player props page at NFL player props. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.