Jacksonville Jaguars vs Denver Broncos Betting Trends

The NFL showdown on December 21, 2025, between the Jacksonville Jaguars and Denver Broncos at Empower Field at Mile High in Denver, CO, is set to be a thrilling Sunday football event. This matchup offers intriguing betting trends to consider for savvy bettors.

Jacksonville’s starting quarterback Trevor Lawrence leads an offense averaging 335.7 total yards per game, with a strong passing game that averages 215 yards. Their run game complements well with 120.7 rushing yards per game. Denver counters with Bo Nix under center, boasting 345.5 total yards per game, slightly higher than Jacksonville, with a balanced attack of 226 passing yards and 119.5 rushing yards. The Broncos’ pass protection faces a formidable challenge against Jacksonville’s aggressive pass rush, which could influence the game's pace and scoring.

Defensively, Denver allows 287.7 total yards per game, slightly more than Jacksonville’s 308.5 yards. Jacksonville’s defense excels in pass rush with 14.2 sacks, while Denver’s defense is solid in third-down defense. Key injuries include Denver’s questionable guard Ben Powers and linebacker Karene Reid, while Jacksonville’s offensive line has a questionable player Ezra Cleveland, though he is likely to play given recent practice reports.

The point spread currently favors Denver by 3.5 points with the total set at 47 points. This spread suggests a close game with moderate scoring expected, aligning with recent games where both teams have seen varied outcomes against the spread and totals. Jacksonville holds a better ATS record (9-5) compared to Denver (6-8), which bettors should consider.

Jacksonville has dominated recent matchups, including a 21-17 loss against Denver in their last meeting in 2022, which you can review for more context. The game will be broadcast on FOX, offering fans and bettors a prime viewing experience.

These betting insights and game stats provide a solid foundation for making informed wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.