Kansas City Chiefs vs Tennessee Titans Betting Trends

The upcoming NFL regular season Week 16 matchup on December 21, 2025, features the Kansas City Chiefs visiting the Tennessee Titans at Nissan Stadium in Nashville, TN. This Sunday football game promises an intense battle as both teams look to improve their standings in the league. Kansas City Chiefs, led by star quarterback Patrick Mahomes, bring a potent offense that averages 23.43 points per game and 357.9 total yards, with a strong passing game supported by 244 passing yards per contest. The Chiefs' offensive line has shown solid pass protection, crucial against a Titans pass rush that averages 2.43 sacks per game.

The Tennessee Titans, starting quarterback Cam Ward, have struggled this season with a 2-12 straight-up record but hold a slightly better ATS record at 6-8. Tennessee's defense allows 28.14 points per game and 356.6 total yards, showing vulnerability that Kansas City's offense will aim to exploit. The Titans' run offense, averaging 20.8 rushing yards per game, faces a stout Chiefs run defense that holds opponents to just 99 rushing yards per game. This matchup's current betting line favors the Chiefs by 2.5 points with a total points over/under set at 37.5, indicating a moderately low-scoring game expected by sportsbooks.

Injuries could play a role: the Chiefs have key players like cornerback Trent McDuffie and linebacker Leo Chenal out, while the Titans have several questionable statuses including tight end Gunnar Helm and cornerback Jalyn Armour-Davis. The TV broadcast on CBS ensures fans can catch all the action live. Bettors should consider these factors and recent performances, such as the Chiefs' recent losses and close games, and the Titans' mixed results, to make informed wagers. Kansas City's strong passing attack versus Tennessee's pass defense and Tennessee's run game against Kansas City's defense will be key battle points.

For those looking to dive deeper into betting trends and game insights, the previous matchup on November 6, 2022, where the Chiefs edged out the Titans 20-17, offers valuable context. The Chiefs have struggled against the spread recently, going 5-9, while the Titans have a slightly better ATS record at 6-8. The total points have often stayed under in their meetings, aligning with the current under 37.5 total points line.

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