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The highly anticipated NFL clash between the Las Vegas Raiders and the Indianapolis Colts is set to kick off on October 5, 2025, at Lucas Oil Stadium in Indianapolis, IN. As the Colts prepare to defend their home turf, the Raiders are eager to make their mark. With the game airing on FOX, fans can tune in for all the live action. Currently, the Colts are favored with a point spread of -7 -118, while the Raiders hold a spread of +7 -105, as per Caesars. These odds suggest a close match, with the Colts having the upper hand. The opening odds were slightly more favorable for the Colts, indicating a shift in expectations as game day approaches.
For those looking to place a bet, the best odds for the Colts are at -350 with Caesars, while the Raiders offer a tempting +260 on the moneyline. The over/under is set at 48, offering bettors an interesting angle on the game's potential scoring. This matchup is crucial for both teams as they aim to climb the NFL standings. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Cleveland 1-363% +3½ -110BetMGM | |||||||
Carolina 1-363% +1½ -110BetRivers | |||||||
![]() N.Y. Jets 0-477% +1½ -105FanDuel | |||||||
![]() Indianapolis 3-131% -7 -110FanDuel | |||||||
Philadelphia 4-033% -4 -110Caesars | |||||||
New Orleans 0-449% -1½ -110BetMGM | |||||||
![]() Baltimore 1-334% +2 -120BetMGM | |||||||
Arizona 2-232% -7½ -109BetRivers | |||||||
Seattle 3-165% -3½ -110Caesars | |||||||
![]() Cincinnati 2-284% +10½ -114BetRivers | |||||||
![]() L.A. Chargers 3-142% -2½ -120FanDuel | |||||||
Buffalo 4-022% -8 -105Caesars | |||||||
Jacksonville 3-183% +3½ -115Caesars | |||||||
![]() L.A. Rams 3-223 -7½ -115FanDuel |
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