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The Las Vegas Raiders vs Indianapolis Colts matchup on October 5, 2025, promises to be a thrilling NFL encounter at Lucas Oil Stadium in Indianapolis, IN. With both teams bringing their A-game, fans can expect high-octane action broadcasted live on FOX. The Raiders will rely on Geno Smith's dual-threat capabilities, with our player projections favoring the Over 246.5 on his total passing and rushing yards, boasting a solid 68.4% hit rate. Meanwhile, the Colts' Daniel Jones is poised for an explosive performance, with projections also indicating he will surpass 253.5 total yards, supported by a 66.5% hit rate. Our prop bets suggest strong value in these markets, especially given the Colts' formidable pass offense against the Raiders' defense.
Pace of play will be crucial, with both teams likely to exploit their running backs. Jonathan Taylor of the Colts is projected to go Over 107.5 rushing and receiving yards, making him a key player to watch. As for the Raiders, Jakobi Meyers' longest reception is another prop bet with high EV, expected to exceed 22.5 yards. This clash is not just about player stats; it's a strategic battle of pass protection versus pass rush, as the Colts' offensive line aims to fend off the Raiders' aggressive pass rush.
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Cleveland 1-363% +3½ -110BetMGM | |||||||
Carolina 1-363% +1½ -110BetRivers | |||||||
![]() N.Y. Jets 0-477% +1½ -105FanDuel | |||||||
![]() Indianapolis 3-131% -7 -110FanDuel | |||||||
Philadelphia 4-033% -4 -110Caesars | |||||||
New Orleans 0-449% -1½ -110BetMGM | |||||||
![]() Baltimore 1-334% +2 -120BetMGM | |||||||
Arizona 2-232% -7½ -109BetRivers | |||||||
Seattle 3-165% -3½ -110Caesars | |||||||
![]() Cincinnati 2-284% +10½ -114BetRivers | |||||||
![]() L.A. Chargers 3-142% -2½ -120FanDuel | |||||||
Buffalo 4-022% -8 -105Caesars | |||||||
Jacksonville 3-183% +3½ -115Caesars | |||||||
![]() L.A. Rams 3-223 -7½ -115FanDuel |
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