Oct 12, 2025 4:25 PM EDT

Week 6

San Francisco

4-1

Tampa Bay

-3½ (-111)o47½ (-107)

CBS

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Injury Report: 49ers vs Buccaneers Clash

Updated:Oct 11, 2025 2:34 AM EDT

Get ready for some Sunday night football as the San Francisco 49ers take on the Tampa Bay Buccaneers at Raymond James Stadium in Tampa, FL, on October 12, 2025. This NFL clash promises to be a thrilling encounter despite the injury woes plaguing both teams. The 49ers will miss key players like Brock Purdy and Jordan Watkins, impacting their offensive and defensive strategies. Meanwhile, the Buccaneers will have to adjust without Mike Evans and Chris Godwin Jr., which could hinder their passing game.

Both teams have significant injuries, with the 49ers' George Kittle potentially returning for their next game, while the Buccaneers' Calijah Kancey might return for the playoffs. These injuries could influence betting odds, making it crucial for bettors to stay informed. Tune in to CBS to catch the action live and use these insights to make smarter bets.

Check out our NFL injury updates for the latest on player statuses. Whether you're a seasoned bettor or new to the game, understanding player injuries can give you the edge in making informed wagers. For those looking to elevate their betting experience, explore OddsTrader Turbo for comprehensive insights and analytics.

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OFFENSE DEPTH CHART

QUARTERBACK

PRIORITY

Brock
Purdy

48/73

586

Out

Mac
Jones

86/129

905

Questionable

Adrian
Martinez

No information available

4 Quarterback

WIDE RECEIVER

Ricky
Pearsall

20-29

327

16.4

Out

Jauan
Jennings

9-19

129

14.3

Questionable

Kendrick
Bourne

18-24

229

12.7

84 Wide Receiver

Marquez
Valdes-Scantling

2-5

9.0

83 Wide Receiver

Demarcus
Robinson

4-9

14.8

5 Wide Receiver

Skyy
Moore

1-2

10.0

9 Wide Receiver

Jordan
Watkins

No information available

Out

LEFT TACKLE

Trent
Williams

71 Offensive Tackle

CENTER

Jake
Brendel

64 Offensive Line

Matt
Hennessy

61 Offensive Line

RIGHT TACKLE

Colton
McKivitz

68 Offensive Line

Austen
Pleasants

62 Offensive Line

RUNNING BACK

Christian
McCaffrey

282

3.1

23 RB

Kyle
Juszczyk

-1

-1.0

44 Fullback

Brian
Robinson Jr.

108

4.0

3 Running Back

Isaac
Guerendo

No information available

31 RB

Jordan
James

No information available

29 Running Back

TIGHT END

Jake
Tonges

19-27

166

8.7

88 Tight End

Luke
Farrell

6-8

7.8

89 Tight End

Brayden
Willis

No information available

82 Tight End

LEFT GUARD

Connor
Colby

75 Offensive Line

RIGHT GUARD

Dominick
Puni

77 Offensive Line

Drew
Moss

65 Offensive Line

DEFENSE DEPTH CHART

LEFT END

Bryce
Huff

8-5

47 Defensive Line

Yetur
Gross-Matos

1-3

Out

Robert
Beal Jr.

No information available

51 Defensive Line

DEFENSIVE TACKLE

Kalia
Davis

3-4

Questionable

Jordan
Elliott

2-9

92 Defensive Line

Alfred
Collins

2-3

Questionable

C.J.
West

1-1

99 Defensive Tackle

LEFT CORNERBACK

Renardo
Green

0 Cornerback

Darrell
Luter Jr.

No information available

28 Cornerback

SAFETY

Jason
Pinnock

No information available

25 Safety

Marques
Sigle

36 Safety

Siran
Neal

No information available

33 Cornerback

Ji'Ayir
Brown

27 Safety

RIGHT END

Mykel
Williams

7-3

98 Defensive Line

Sam
Okuayinonu

7-9

91 Defensive Line

LINEBACKER

Dee
Winters

27-9

53 Linebacker

Fred
Warner

28-22

54 Linebacker

Upton
Stout

10-10

Questionable

Tatum
Bethune

No information available

48 Linebacker

Luke
Gifford

No information available

57 Linebacker

Curtis
Robinson

No information available

59 Linebacker

Nick
Martin

No information available

45 Linebacker

RIGHT CORNERBACK

Deommodore
Lenoir

2 Defensive Back

Chase
Lucas

No information available

26 Cornerback

SPECIAL TEAMS DEPTH CHART

KICKER

Eddy
Pineiro

18 Kicker

PUNTER

Thomas
Morstead

43.7

7 P

HOLDER

Thomas
Morstead

7 P

KICK RETURNER

Isaac
Guerendo

20.0

31 RB

Skyy
Moore

24.4

9 Wide Receiver

PUNT RETURNER

Skyy
Moore

8.2

9 Wide Receiver

Jordan
Watkins

No information available

Out

Ricky
Pearsall

No information available

Out

LONG SNAPPER

Jon
Weeks

46 Long Snapper

Additional Injuries

PRIORITY

Brandon Aiyuk

11 Wide Receiver

16 days ago

PUP

Est. Return Oct 12, 2025

49ers GM John Lynch said Thursday that Aiyuk (knee, PUP) is "not close" to returning, David Lombardi of SFStandard.com reports. More Details

George Kittle

85 Tight End

3 days ago

Injury Reserve

Est. Return Oct 19, 2025

San Francisco head coach Kyle Shanahan said Wednesday that there's a chance Kittle (hamstring) could return from IR in time to play Week 7 against the Falcons, David Lombardi of SFStandard.com reports. More Details

Trent Taylor

81 Wide Receiver

4 months ago

Injury Reserve

Est. Return Feb 9, 2026

The 49ers placed Taylor (undisclosed) on injured reserve Tuesday. More Details

Kevin Givens

90 Defensive Line

9 hours ago

IR-R

Est. Return Oct 19, 2025

Givens (pectoral) is out for Sunday's game against Tampa Bay, Greg Auman of Fox Sports reports. More Details

Nick Bosa

97 Defensive Line

14 days ago

Injury Reserve

Est. Return Feb 9, 2026

Bosa (knee) underwent surgery to address his torn ACL on Friday, Cam Inman of The San Jose Mercury News reports. More Details

Patrick Taylor Jr.

32 Running Back

2 months ago

Injury Reserve

Est. Return Feb 9, 2026

Taylor will undergo season-ending surgery to repair a fracture in his shoulder, Nick Wagoner of ESPN.com reports. More Details

Tre Tomlinson

35 Cornerback

5 months ago

Injury Reserve

Est. Return Feb 9, 2026

Tomlinson (undisclosed) reverted to the 49ers' injured reserve Tuesday, per the NFL's transaction log. More Details

Jacob Cowing

19 Wide Receiver

a month ago

Injury Reserve

Est. Return Oct 12, 2025

The 49ers placed Cowing (hamstring) on injured reserve Wednesday. More Details

Malik Mustapha

6 Safety

8 hours ago

PUP

Est. Return Oct 12, 2025

Mustapha (knee) is listed as questionable for Sunday's game against the Buccaneers, Greg Auman of Fox Sports reports. More Details

Jakob Robinson

49 Cornerback

a month ago

Injury Reserve

Est. Return Feb 9, 2026

Robinson (forearm) was placed on injured reserve Tuesday. More Details

Kurtis Rourke

4 Quarterback

a month ago

NFI-R

Est. Return Oct 12, 2025

Rourke (knee) was placed on the reserve/non-football injury list Tuesday. More Details

Ben Bartch

78 Offensive Line

23 days ago

Injury Reserve

Est. Return Oct 19, 2025

Bartch (ankle) was placed on injured reserve Wednesday, Noah Furtado of the San Francisco Chronicle reports. More Details

Isaac Alarcon

67 Offensive Line

6 months ago

RESERVE-SUS

Est. Return Oct 19, 2025

Alarcon was handed a six-game suspension Wednesday for violating the NFL's performance-enhancing substances policy, Matt Maiocco of NBC Sports Bay Area reports. More Details

Tarron Jackson

56 Defensive Line

2 months ago

Injury Reserve

Est. Return Feb 9, 2026

The 49ers placed Jackson (undisclosed) on injured reserve Tuesday. More Details

Spencer Burford

74 Offensive Line

20 days ago

Injury Reserve

Est. Return Oct 19, 2025

Burford (knee) was placed on injured reserve Saturday. More Details

NFL

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Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/129:30 AM Denver 3-2 29% -7 -106BetRivers
N.Y. Jets 0-5 71% +7½ -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Cleveland 1-4 61% +6 -110Bet365
Pittsburgh 3-1 39% -5½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Arizona 2-3 69% +7 -102BetMGM
Indianapolis 4-1 31% -7 -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM L.A. Rams 3-2 34% -7 -112Caesars
Baltimore 1-4 66% +7½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Seattle 3-2 22% +1 -115Bet365
Jacksonville 4-1 78% +1½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM Dallas 2-2-1 21% -3 -109Caesars
Carolina 2-3 79% +3 -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM L.A. Chargers 3-2 35% -3½ -113BetRivers
Miami 1-4 65% +4½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/121:00 PM New England 3-2 40% -3½ +100Caesars
New Orleans 1-4 60% +3½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/124:05 PM Tennessee 1-4 66% +4½ -115FanDuel
Las Vegas 1-4 34% -4 -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/124:25 PM San Francisco 4-1 62% +3½ -111Caesars
Tampa Bay 4-1 38% -3 -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/124:25 PM Cincinnati 2-3 69% +14½ -110BetMGM
Green Bay 2-1-1 31% -14½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 10/128:20 PM Detroit 4-1 67% +2½ -110Caesars
Kansas City 2-3 33% -2 -113SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. MON 10/137:15 PM Buffalo 4-1 16% -4½ -109BetRivers
Atlanta 2-2 84% +5 -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. MON 10/138:15 PM Chicago 2-2 76% +4½ -110Caesars
Washington 3-2 24% -4½ -108BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 10/098:15 PM Philadelphia 4-2 17 -7½ +100BetMGM
N.Y. Giants 2-4 34 +7½ -105BetMGM

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