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NFL Week 4 Odds: Best Lines Available

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A detailed view of the flags of the United Kingdom and the United States inside the stadium prior to the NFL match between New York Giants and Green Bay Packers at Tottenham Hotspur Stadium on October 09, 2022. Mike Hewitt/Getty Images/AFP

Week 4 of the 2023 NFL regular season brings a lineup of exciting games. The action begins Thursday, September 28 with an NFC North matchup between the Detroit Lions and the Green Bay Packers at Lambeau Field.

The Lions are motivated to reverse their fortunes and start a new era against the Packers now led by Jordan Love.

Football fans in London can anticipate an enticing game on Sunday as the Atlanta Falcons and the Jacksonville Jaguars clash in the first of two consecutive games that the Jags will play abroad. With a 9:30 AM ET start time, remember to set your alarm to catch this early matchup.

In the US, 6 divisional matchups take the spotlight. Notable games include the Miami Dolphins against the Buffalo Bills, the Baltimore Ravens visiting the Cleveland Browns, and the Tampa Bay Buccaneers traveling to New Orleans to face the Saints, all during the 1 PM slate.

Sunday Night Football features the Kansas City Chiefs taking on the New York Jets.

Lastly, the New York Giants return home to host the Seattle Seahawks on MNF after a two-week stint on the West Coast. With both teams eager to regain momentum, this matchup holds the potential for a thrilling contest.

NFL Week 4 Odds

Below is the complete list of NFL Week 4 odds.

Matchup Date Time Spread Over/Under
Cowboys vs. Giants Thursday, September 26 08:15 PM ET Cowboys -5 (-120) 45.5
Steelers vs. Colts Sunday, September 29 01:00 PM ET Colts -1 (-120) 44.5
Vikings vs. Packers Sunday, September 29 01:00 PM ET Packers -5.5 (-120) 46
Jaguars vs. Texans Sunday, September 29 01:00 PM ET Texans -3.5 (-120) 47
Saints vs. Falcons Sunday, September 29 01:00 PM ET Falcons -3.5 (-120) 45
Rams vs. Bears Sunday, September 29 01:00 PM ET Bears -1 (-120) 47.5
Eagles vs. Buccaneers Sunday, September 29 01:00 PM ET Eagles -3 (-120) 48
Bengals vs. Panthers Sunday, September 29 01:00 PM ET Bengals -5.5 (-120) 45.5
Broncos vs. Jets Sunday, September 29 01:00 PM ET Jets -6.5 (-120) 43
Commanders vs. Cardinals Sunday, September 29 01:00 PM ET Cardinals -3 (-120) 46
Patriots vs. 49ers Sunday, September 29 04:05 PM ET 49ers -12 (-120) 43.5
Browns vs. Raiders Sunday, September 29 04:05 PM ET Browns -1 (-120) 44
Chiefs vs. Chargers Sunday, September 29 04:25 PM ET Chiefs -3.5 (-120) 48.5
Bills vs. Ravens Sunday, September 29 04:25 PM ET Ravens -3.5 (-120) 46.5
Titans vs. Dolphins Monday, September 30 07:30 PM ET Dolphins -6.5 (-120) 47
Seahawks vs. Lions Monday, September 30 08:15 PM ET Lions -6 (-120) 49

*Odds via Caesars Sportsbook (check our Caesars Sportsbook Review) 

Best NFL Week 4 Spread Available

Matchup Current Best Spread Available
Cowboys vs. Giants Cowboys -5 (-120) at Caesars Sportsbook
Steelers vs. Colts Colts -1 (-120) at Caesars Sportsbook
Vikings vs. Packers Packers -5.5 (-120) at Caesars Sportsbook
Jaguars vs. Texans Texans -3.5 (-120) at Caesars Sportsbook
Saints vs. Falcons Falcons -3.5 (-120) at Caesars Sportsbook
Rams vs. Bears Bears -1 (-120) at Caesars Sportsbook
Eagles vs. Buccaneers Eagles -3 (-120) at Caesars Sportsbook
Bengals vs. Panthers Bengals -5.5 (-120) at Caesars Sportsbook
Broncos vs. Jets Jets -6.5 (-120) at Caesars Sportsbook
Commanders vs. Cardinals Cardinals -3 (-120) at Caesars Sportsbook
Patriots vs. 49ers 49ers -12 (-120) at Caesars Sportsbook
Browns vs. Raiders Browns -1 (-120) at Caesars Sportsbook
Chiefs vs. Chargers Chiefs -3.5 (-120) at Caesars Sportsbook
Bills vs. Ravens Ravens -3.5 (-120) at Caesars Sportsbook
Titans vs. Dolphins Dolphins -6.5 (-120) at Caesars Sportsbook
Seahawks vs. Lions Lions -6 (-120) at Caesars Sportsbook

More Weekly NFL Odds Previews

Eager to explore the upcoming NFL schedule for the most recent odds or curious about the odds of a game that has already taken place? Check out our odds preview covering all 18 weeks of the NFL regular season!

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