NFL Week 4 will treat us to some incredible football games to bet on, including the Chiefs visiting the Buccaneers in another chapter of the Mahomes-Brady rivalry. Below you can check out the latest odds for all Week 4 clashes.
Week 4 has many games with betting potential, including the Bills visiting the Ravens and the Broncos-Raiders battle in Las Vegas.
Here is the full slate of games and the latest NFL Week 4 odds.
NFL Week 4 Odds
These are the NFL
| Matchup | Time | Spread | Over/Under |
|---|---|---|---|
| Steelers vs. Browns | Thursday, September 29, 2022 – 08:15 PM EST at Paul Brown Stadium | Browns -3.5 | N/A |
| Saints vs. Panthers | Sunday, October 2, 2022 – 09:30 AM EST at Tottenham Hotspur Stadium | Saints -1.5 | N/A |
| Texans vs. Bears | Sunday, October 2, 2022 – 01:00 PM EST at Mercedes-Benz Stadium | Bears -3.5 | N/A |
| Chiefs vs. Colts | Sunday, October 2, 2022 – 01:00 PM EST at M&T Bank Stadium | Chiefs -2.5 | N/A |
| Bills vs. Dolphins | Sunday, October 2, 2022 – 01:00 PM EST at AT&T Stadium | Bills -4 | N/A |
| Lions vs. Vikings | Sunday, October 2, 2022 – 01:00 PM EST at Ford Field | Vikings -6.5 | N/A |
| Ravens vs. Patriots | Sunday, October 2, 2022 – 01:00 PM EST at NRG Stadium | Patriots PK | N/A |
| Bengals vs. Jets | Sunday, October 2, 2022 – 01:00 PM EST at Lucas Oil Stadium | Bengals -4.5 | N/A |
| Raiders vs. Titans | Sunday, October 2, 2022 – 01:00 PM EST at MetLife Stadium | Titans -2.5 | N/A |
| Eagles vs. Commanders | Sunday, October 2, 2022 – 01:00 PM EST at Lincoln Financial Field | Eagles -2.5 | N/A |
| Jaguars vs. Chargers | Sunday, October 2, 2022 – 01:00 PM EST at Acrisure Stadium | Chargers -10 | N/A |
| Rams vs. Cardinals | Sunday, October 2, 2022 – 04:05 PM EST at Bank of America Stadium | Rams -1 | N/A |
| Falcons vs. Seahawks | Sunday, October 2, 2022 – 04:25 PM EST at Lambeau Field | Seahawks -3.5 | N/A |
| Packers vs. Buccaneers | Sunday, October 2, 2022 – 04:25 PM EST at Allegiant Stadium | Buccaneers -3 | 52 |
| 49ers vs. Broncos | Sunday, October 2, 2022 – 08:20 PM EST at Raymond James Stadium | Broncos -3 | 46.5 |
| Cowboys vs. Giants | Monday, October 3, 2022 – 08:15 PM EST at Levi’s Stadium | Cowboys -3 | 48 |
| Matchup | Best Spread Available |
|---|---|
| Dolphins vs. Bengals | Bengals -4 at Caesars Sportsbook |
| Vikings vs. Saints | Vikings +1 at FanDuel |
| Browns vs. Falcons | Browns -2.5 at Caesars Sportsbook |
| Bills vs. Ravens | Bills -1 at DraftKings |
| Commanders vs. Cowboys | Cowboys -6 at Caesars Sportsbook |
| Seahawks vs. Lions | Lions -1 at DraftKings |
| Chargers vs. Texans | Chargers -8 at DraftKings |
| Titans vs. Colts | Colts -3 at Caesars Sportsbook |
| Bears vs. Giants | Giants -2.5 at DraftKings |
| Jaguars vs. Eagles | Eagles -6.5 at DraftKings |
| Jets vs. Steelers | Steelers -3.5 at DraftKings |
| Cardinals vs. Panthers | Cardinals -1.5 at DraftKings |
| Patriots vs. Packers | Packers -5 at DraftKings |
| Broncos vs. Raiders | Raiders PK at Caesars Sportsbook |
| Chiefs vs. Buccaneers | Buccaneers -2.5 at Unibet |
| Rams vs. 49ers | Rams PK at Caesars Sportsbook |
