NFL Week 5 will deliver plenty of excitement, including a London game, the Cowboys visit to the Rams and the Bengals-Ravens game on Sunday Night Football. Below you can check out the latest odds for all Week 5 clashes.
We are in for some great betting action. In addition to the Cowboys-Rams game in Los Angeles, another can’t-miss contest is the AFC West battle between the Raiders and Chiefs on Monday Night Football.
Here is the full slate of games and the latest NFL Week 5 odds.
NFL Week 5 Odds
These are the NFL odds for Week 5, headlined by the Giants vs. Packers game in London.
| Matchup | Time | Spread | Over/Under |
|---|---|---|---|
| Colts vs. Broncos | Thursday, October 6, 2022 – 08:15 PM EST at Empower Field at Mile High | Broncos -3.5 | 44 |
| Giants vs. Packers | Sunday, October 9, 2022 – 09:30 AM EST at Tottenham Hotspur Stadium | Packers -7 | 45.5 |
| Steelers vs. Bills | Sunday, October 9, 2022 – 01:00 PM EST at Highmark Stadium | Bills -9 | N/A |
| Chargers vs. Browns | Sunday, October 9, 2022 – 01:00 PM EST at FirstEnergy Stadium | Chargers -3 | N/A |
| Texans vs. Jaguars | Sunday, October 9, 2022 – 01:00 PM EST TIAA Bank Field | Jaguars -3.5 | N/A |
| Bears vs. Vikings | Sunday, October 9, 2022 – 01:00 PM EST at U.S. Bank Stadium | Vikings -6 | N/A |
| Lions vs. Patriots | Sunday, October 9, 2022 – 01:00 PM EST at Gillette Stadium | Patriots -6.5 | N/A |
| Seahawks vs. Saints | Sunday, October 9, 2022 – 01:00 PM EST at Caesars Superdome | Saints -5 | N/A |
| Dolphins vs. Jets | Sunday, October 9, 2022 – 01:00 PM EST at MetLife Stadium | Dolphins -3 | N/A |
| Falcons vs. Buccaneers | Sunday, October 9, 2022 – 01:00 PM EST at Raymond James Stadium | Buccaneers -11 | N/A |
| Titans vs. Commanders | Sunday, October 9, 2022 – 01:00 PM EST at FedExField | Commanders -1 | N/A |
| 49ers vs. Panthers | Sunday, October 9, 2022 – 04:05 PM EST at Bank of America Stadium | 49ers -3 | N/A |
| Eagles vs. Cardinals | Sunday, October 9, 2022 – 04:25 PM EST at State Farm Stadium | Cardinals -2.5 | N/A |
| Cowboys vs. Rams | Sunday, October 9, 2022 – 04:25 PM EST at SoFi Stadium | Rams -5.5 | 52.5 |
| Bengals vs. Ravens | Sunday, October 9, 2022 – 08:20 PM EST at M&T Bank Stadium | Ravens -2.5 | 45 |
| Raiders vs. Chiefs | Monday, October 10, 2022 – 08:15 PM EST at GEHA Field at Arrowhead Stadium | Chiefs -6 | 52.5 |
| Matchup | Best Spread Available |
|---|---|
| Colts vs. Broncos | Broncos -3 at DraftKings |
| Giants vs. Packers | Packers -6.5 at FanDuel |
| Steelers vs. Bills | Bills -9 at Caesars Sportsbook |
| Chargers vs. Browns | Chargers -3 at Caesars Sportsbook |
| Texans vs. Jaguars | Jaguars -3.5 at Caesars Sportsbook |
| Bears vs. Vikings | Vikings -6 at Caesars Sportsbook |
| Lions vs. Patriots | Patriots -6.5 at Caesars Sportsbook |
| Seahawks vs. Saints | Saints 5 at Caesars Sportsbook |
| Dolphins vs. Jets | Dolphins -2.5 at DraftKings |
| Falcons vs. Buccaneers | Buccaneers -10.5 at DraftKings |
| Titans vs. Commanders | Commanders PK at DraftKings |
| 49ers vs. Panthers | 49ers -2.5 at DraftKings |
| Eagles vs. Cardinals | Cardinals -2 at DraftKings |
| Cowboys vs. Rams | Rams -4.5 at DraftKings |
| Bengals vs. Ravens | Ravens -1 at DraftKings |
| Raiders vs. Chiefs | Chiefs -6 at Caesars Sportsbook |
