Nov 16, 2025 4:05 PM EST

Week 11

San Francisco

2-2

Arizona

-1½ (-115)o47½ (-115)

FOX

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49ers vs Cardinals Injury Report

Review all Week 11 NFL injuries for the 49ers vs Cardinals game Nov 16, 2025 including players who are Out, Doubtful or Questionable.

(SF) Brock Purdy is QUESTIONABLE and (ARI) James Conner is IR. See all 47 injuries below from both teams for this game. This injury report was updated 10 hours ago.

What are the odds for this game?

ARI

OFFENSE DEPTH CHART

QUARTERBACK

PRIORITY

Brock
Purdy

26/35

277

Questionable

Mac
Jones

53/80

563

Questionable

WIDE RECEIVER

Ricky
Pearsall

16-24

281

17.6

Questionable

Jauan
Jennings

7-15

105

15.0

Questionable

Demarcus
Robinson

No information available

5 Wide Receiver

Marquez
Valdes-Scantling

1-2

9.0

83 Wide Receiver

Skyy
Moore

1-1

10.0

9 Wide Receiver

Kendrick
Bourne

7-9

10.0

84 Wide Receiver

Jordan
Watkins

No information available

Questionable

LEFT TACKLE

Trent
Williams

71 Offensive Tackle

CENTER

Jake
Brendel

64 Offensive Line

Matt
Hennessy

61 Offensive Line

RIGHT TACKLE

Colton
McKivitz

68 Offensive Line

Austen
Pleasants

62 Offensive Line

RUNNING BACK

Kyle
Juszczyk

No information available

44 Fullback

Christian
McCaffrey

176

3.4

23 RB

Brian
Robinson Jr.

4.4

3 Running Back

Isaac
Guerendo

No information available

31 RB

Jordan
James

No information available

29 Running Back

TIGHT END

Jake
Tonges

9-11

7.4

88 Tight End

Luke
Farrell

3-4

6.3

89 Tight End

Brayden
Willis

No information available

82 Tight End

LEFT GUARD

Connor
Colby

Questionable

RIGHT GUARD

Dominick
Puni

77 Offensive Line

Drew
Moss

65 Offensive Line

DEFENSE DEPTH CHART

LEFT END

Bryce
Huff

5-4

47 Defensive Line

Yetur
Gross-Matos

No information available

Questionable

Robert
Beal Jr.

No information available

51 Defensive Line

DEFENSIVE TACKLE

Jordan
Elliott

1-7

92 Defensive Line

Kalia
Davis

2-3

93 Defensive Line

Alfred
Collins

No information available

95 Defensive Tackle

C.J.
West

1-1

Questionable

Jordan
Jefferson

No information available

96 Defensive Tackle

LEFT CORNERBACK

Renardo
Green

Questionable

Chase
Lucas

No information available

26 Cornerback

SAFETY

Marques
Sigle

No information available

36 Safety

Jason
Pinnock

No information available

25 Safety

Ji'Ayir
Brown

27 Safety

Siran
Neal

No information available

33 Cornerback

RIGHT END

Mykel
Williams

6-2

98 Defensive End

Sam
Okuayinonu

4-6

91 Defensive Line

LINEBACKER

Fred
Warner

16-14

54 Linebacker

Dee
Winters

15-7

53 Linebacker

Upton
Stout

8-3

20 Cornerback

Luke
Gifford

No information available

57 Linebacker

Tatum
Bethune

No information available

48 Linebacker

Nick
Martin

No information available

45 Linebacker

Curtis
Robinson

No information available

59 Linebacker

RIGHT CORNERBACK

Deommodore
Lenoir

No information available

Questionable

Darrell
Luter Jr.

No information available

28 Cornerback

SPECIAL TEAMS DEPTH CHART

KICKER

Eddy
Pineiro

18 Kicker

PUNTER

Thomas
Morstead

44.1

7 P

HOLDER

Thomas
Morstead

7 P

KICK RETURNER

Isaac
Guerendo

20.5

31 RB

Skyy
Moore

28.3

9 Wide Receiver

PUNT RETURNER

Skyy
Moore

8.3

9 Wide Receiver

Jordan
Watkins

No information available

Questionable

Ricky
Pearsall

No information available

Questionable

LONG SNAPPER

Jon
Weeks

46 Long Snapper

Additional Injuries

PRIORITY

George Kittle

85 Tight End

17 days ago

Injury Reserve

Est. Return Oct 12, 2025

The 49ers placed Kittle (hamstring) on injured reserve Tuesday. More Details

PRIORITY

Brandon Aiyuk

11 Wide Receiver

21 hours ago

PUP

Est. Return Oct 2, 2025

49ers GM John Lynch said Thursday that Aiyuk (knee, PUP) is "not close" to returning, David Lombardi of SFStandard.com reports. More Details

Nick Bosa

97 Defensive Line

17 hours ago

Injury Reserve

Est. Return Feb 9, 2026

The 49ers placed Bosa (knee) on injured reserve Thursday. More Details

Trent Taylor

81 Wide Receiver

4 months ago

Injury Reserve

Est. Return Feb 9, 2026

The 49ers placed Taylor (undisclosed) on injured reserve Tuesday. More Details

Kevin Givens

90 Defensive Line

a month ago

IR-R

Est. Return Oct 2, 2025

Givens (pectoral) was placed on injured reserve Tuesday. More Details

Patrick Taylor Jr.

32 Running Back

a month ago

Injury Reserve

Est. Return Feb 9, 2026

Taylor will undergo season-ending surgery to repair a fracture in his shoulder, Nick Wagoner of ESPN.com reports. More Details

Tre Tomlinson

35 Cornerback

4 months ago

Injury Reserve

Est. Return Feb 9, 2026

Tomlinson (undisclosed) reverted to the 49ers' injured reserve Tuesday, per the NFL's transaction log. More Details

Jacob Cowing

19 Wide Receiver

a month ago

Injury Reserve

Est. Return Oct 2, 2025

The 49ers placed Cowing (hamstring) on injured reserve Wednesday. More Details

Malik Mustapha

6 Safety

a month ago

PUP

Est. Return Oct 2, 2025

Mustapha (knee) was placed on the reserve/PUP list Tuesday. More Details

Jakob Robinson

49 Cornerback

a month ago

Injury Reserve

Est. Return Feb 9, 2026

Robinson (forearm) was placed on injured reserve Tuesday. More Details

Kurtis Rourke

4 Quarterback

a month ago

NFI-R

Est. Return Oct 2, 2025

Rourke (knee) was placed on the reserve/non-football injury list Tuesday. More Details

Ben Bartch

78 Offensive Line

9 days ago

Injury Reserve

Est. Return Oct 19, 2025

Bartch (ankle) was placed on injured reserve Wednesday, Noah Furtado of the San Francisco Chronicle reports. More Details

Isaac Alarcon

67 Offensive Line

5 months ago

RESERVE-SUS

Est. Return Oct 19, 2025

Alarcon was handed a six-game suspension Wednesday for violating the NFL's performance-enhancing substances policy, Matt Maiocco of NBC Sports Bay Area reports. More Details

Tarron Jackson

56 Defensive Line

2 months ago

Injury Reserve

Est. Return Feb 9, 2026

The 49ers placed Jackson (undisclosed) on injured reserve Tuesday. More Details

Spencer Burford

74 Offensive Line

5 days ago

Injury Reserve

Est. Return Oct 19, 2025

Burford (knee) was placed on injured reserve Saturday. More Details

NFL

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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This Week

Last Week

Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/289:30 AM Minnesota 2-1 56% -2 -120BetMGM
Pittsburgh 2-1 44% +3 -121SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Philadelphia 3-0 36% -3½ -105FanDuel
Tampa Bay 3-0 64% +3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM New Orleans 0-3 68% +15½ -110Bet365
Buffalo 3-0 32% -15 -120BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Carolina 1-2 59% +5½ -109BetRivers
New England 1-2 41% -5½ -106Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Washington 2-1 27% -1 -105BetMGM
Atlanta 1-2 73% +1½ -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Cleveland 1-2 86% +10 -110Bet365
Detroit 2-1 14% -9½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Tennessee 0-3 75% +7½ -122FanDuel
Houston 0-3 25% -7 -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM L.A. Chargers 3-0 23% -6½ -108BetRivers
N.Y. Giants 0-3 77% +6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:05 PM Jacksonville 2-1 65% +3½ -115Caesars
San Francisco 3-0 35% -3 -117BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:05 PM Indianapolis 3-0 66% +3½ -110Caesars
L.A. Rams 2-1 34% -3 -120SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:25 PM Chicago 1-2 42% +1½ -118FanDuel
Las Vegas 1-2 58% -½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:25 PM Baltimore 1-2 40% -2½ -115Caesars
Kansas City 1-2 60% +3 -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/288:20 PM Green Bay 2-1 39% -6½ -110Caesars
Dallas 1-2 61% +7 -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. MON 09/297:15 PM N.Y. Jets 0-3 69% +3 -115BetRivers
Miami 0-3 31% -2½ -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. MON 09/298:15 PM Cincinnati 2-1 92% +7½ -110Caesars
Denver 1-2 8% -7½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 09/258:15 PM Seattle 3-1 23 -1 -110Caesars
Arizona 2-2 20 +2 -109SugarHouse

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