NFL Week 12 Odds: Giants-Cowboys Headlines Action-Packed Thanksgiving Slate

Dak Prescott #4 of the Dallas Cowboys. Tom Pennington/Getty Images/AFP

NFL Week 12 features three Thanksgiving games, including the New York Giants visiting Dak Prescott and the Dallas Cowboys. Other can’t-miss games are Aaron Rodgers and the Packers taking on the Eagles on Sunday Night Football and the Colts playing the Steelers on Monday Night Football. Below you can check out the latest odds for all Week 12 clashes.

The three Thursday Thanksgiving games include the Lions hosting the Bills, the Patriots clashing with the Vikings and the previously mentioned Giants-Cowboys game.

Here is the full slate of games and the latest NFL Week 12 odds

NFL Week 12 Odds

These are the NFL odds for Week 12, headlined by the Rams visiting the Chiefs in a potential Super Bowl LVII preview and the Packers heading to Philadelphia on Sunday night.

MatchupTimeSpreadOver/Under
Bills vs. LionsThursday, November 24, 2022 – 12:30 PM EST at Ford FieldBills -951
Giants vs. CowboysThursday, November 24, 2022 – 04:30 PM EST at AT&T StadiumCowboys -6.547
Patriots vs. VikingsThursday, November 24, 2022 – 08:20 PM EST at U.S. Bank StadiumVikings -248
Broncos vs. PanthersSunday, November 27, 2022 – 01:00 PM EST at Bank of America StadiumBroncos -3N/A
Buccaneers vs. BrownsSunday, November 27, 2022 – 01:00 PM EST at FirstEnergy StadiumBuccaneers -4.5N/A
Ravens vs. JaguarsSunday, November 27, 2022 – 01:00 PM EST at TIAA Bank FieldRavens -4 N/A
Texans vs. DolphinsSunday, November 27, 2022 – 01:00 PM EST at Hard Rock StadiumDolphins -7 N/A
Bears vs. JetsSunday, November 27, 2022 – 01:00 PM EST at MetLife StadiumJets -1.5 N/A
Bengals vs. TitansSunday, November 27, 2022 – 01:00 PM EST at Nissan StadiumTitans PKN/A
Falcons vs. CommandersSunday, November 27, 2022 – 01:00 PM EST at FedExFieldCommanders -4.5 N/A
Chargers vs. CardinalsSunday, November 27, 2022 – 04:05 PM EST at State Farm StadiumChargers -1.5 N/A
Raiders vs. SeahawksSunday, November 27, 2022 – 04:05 PM EST at Lumen FieldRaiders -3  49
Rams vs. ChiefsSunday, November 27, 2022 – 04:25 PM EST at GEHA Field at Arrowhead StadiumChiefs -3 50.5
Saints vs. 49ersSunday, November 27, 2022 – 04:25 PM EST at Levi’s Stadium49ers -4.5  48.5
Packers vs. EaglesSunday, November 27, 2022 – 08:20 PM EST at Lincoln Financial FieldEagles PK 47
Steelers vs. ColtsMonday, November 28, 2022 – 08:15 PM EST at Lucas Oil StadiumColts -5.5 44.5
Odds courtesy of Caesars Sportsbook as of July 22

MatchupBest Spread Available
Bills vs. LionsBills -8 at DraftKings
Giants vs. CowboysCowboys -6.5 at Caesars Sportsbook
Patriots vs. VikingsVikings -1.5 at DraftKings
Broncos vs. PanthersBroncos -2.5 at DraftKings
Buccaneers vs. BrownsBuccaneers -4.5 at Caesars Sportsbook
Ravens vs. JaguarsRavens -4 at Caesars Sportsbook
Texans vs. DolphinsDolphins -7 at Caesars Sportsbook
Bears vs. JetsJets -1.5 at Caesars Sportsbook
Bengals vs. TitansTitans PK at Caesars Sportsbook
Falcons vs. CommandersCommanders -4.5 at Caesars Sportsbook
Chargers vs. CardinalsChargers -1.5 at Caesars Sportsbook
Raiders vs. SeahawksRaiders -2 at DraftKings
Rams vs. ChiefsChiefs -2.5 at DraftKings
Saints vs. 49ers49ers -4 at DraftKings
Packers vs. EaglesEagles PK at Caesars Sportsbook
Steelers vs. ColtsColts -4.5 at DraftKings
Odds as of July 22 

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